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29172484 | Insulin-like Growth Factor 1 Analogs Clicked in the C Domain: Chemical Synthesis and Biological Activities. | 2017 Dec 28 |
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| 2 |
26339260 | Recombinant production of mecasermin in E. coli expression system. | 2014 Nov-Dec |
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| 3 |
22746182 | Redox and metal ion binding properties of human insulin-like growth factor 1 determined by electrospray ionization mass spectrometry. | 2012 Jul 24 |
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19959476 | Contribution of residue B5 to the folding and function of insulin and IGF-I: constraints and fine-tuning in the evolution of a protein family. | 2010 Feb 12 |
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17922544 | Insulin receptor substrate 1 knockdown in human MCF7 ER+ breast cancer cells by nuclease-resistant IRS1 siRNA conjugated to a disulfide-bridged D-peptide analogue of insulin-like growth factor 1. | 2007 Nov-Dec |
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| 6 |
16864583 | The folding nucleus of the insulin superfamily: a flexible peptide model foreshadows the native state. | 2006 Sep 22 |
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| 7 |
16894147 | The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity. | 2006 Aug 15 |
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15567151 | 1.42A crystal structure of mini-IGF-1(2): an analysis of the disulfide isomerization property and receptor binding property of IGF-1 based on the three-dimensional structure. | 2005 Jan 7 |
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| 9 |
11814349 | The different folding behavior of insulin and insulin-like growth factor 1 is mainly controlled by their B-chain/domain. | 2002 Feb 5 |
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12186542 | The different energetic state of the intra A-chain/domain disulfide of insulin and insulin-like growth factor 1 is mainly controlled by their B-chain/domain. | 2002 Aug 27 |
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18759047 | The thermodynamic stability of insulin disulfides is not affected by the C-domain of insulin-like growth factor 1. | 2002 Jun |
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| 12 |
10993229 | Direct identification of a novel disulfide bond linkage system of new isolated isomer (isomer V) in recombinantly produced h-IGF-I. | 2000 Sep |
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| 13 |
11083061 | Three-dimensional solution structure of a disulfide bond isomer of the human insulin-like growth factor-I. | 2000 Oct |
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| 14 |
9951525 | Probing the disulfide folding pathway of insulin-like growth factor-I. | 1999 Mar 20 |
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| 15 |
10025946 | Insulin-like growth factors I and II are unable to form and maintain their native disulfides under in vivo redox conditions. | 1999 Jan 29 |
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| 16 |
10422834 | Analysis of the extent of unfolding of denatured insulin-like growth factor. | 1999 Jul |
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| 17 |
10608814 | Probing the folding pathways of long R(3) insulin-like growth factor-I (LR(3)IGF-I) and IGF-I via capture and identification of disulfide intermediates by cyanylation methodology and mass spectrometry. | 1999 Dec 31 |
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| 18 |
9109671 | Disulfide exchange folding of disulfide mutants of insulin-like growth factor I in vitro. | 1997 Apr 15 |
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9186491 | Putative folding pathway of insulin-like growth factor-I. | 1997 Jun 15 |
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| 20 |
9294820 | Oxidation of human insulin-like growth factor I in formulation studies. 3. Factorial experiments of the effects of ferric ions, EDTA, and visible light on methionine oxidation and covalent aggregation in aqueous solution. | 1997 Sep |
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| 21 |
8662901 | Biosensor measurement of the binding of insulin-like growth factors I and II and their analogues to the insulin-like growth factor-binding protein-3. | 1996 Jun 14 |
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| 22 |
7794252 | The neuroendocrine protein 7B2 acts as a molecular chaperone in the in vitro folding of human insulin-like growth factor-1 secreted from yeast. | 1995 Jun 15 |
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| 23 |
7515683 | Folding of insulin-like growth factor I is thermodynamically controlled by insulin-like growth factor binding protein. | 1994 Jun 7 |
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| 24 |
8257688 | Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification. | 1993 Dec 14 |
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| 25 |
8397784 | Mutation of Arg55/56 to Leu55/Ala56 in insulin-like growth factor-I results in two forms different in disulfide structure and native conformation but similar under reverse-phase conditions. | 1993 Jun |
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| 26 |
8494897 | Oxidative refolding of insulin-like growth factor 1 yields two products of similar thermodynamic stability: a bifurcating protein-folding pathway. | 1993 May 18 |
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| 27 |
8494898 | Role of native disulfide bonds in the structure and activity of insulin-like growth factor 1: genetic models of protein-folding intermediates. | 1993 May 18 |
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| 28 |
1320041 | Insulin/IGF-I receptor hybrids: a mechanism for increasing receptor diversity. | 1992 Feb |
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| 29 |
1483466 | A mutant Kex2 enzyme with a C-terminal HDEL sequence releases correctly folded human insulin-like growth factor-1 from a precursor accumulated in the yeast endoplasmic reticulum. | 1992 Dec 15 |
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| 30 |
1606975 | Disulfide arrangement of human insulin-like growth factor I derived from yeast and plasma. | 1992 Jun 15 |
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| 31 |
1618297 | A modified Kex2 enzyme retained in the endoplasmic reticulum prevents disulfide-linked dimerisation of recombinant human insulin-like growth factor-1 secreted from yeast. | 1992 Jun 8 |
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| 32 |
1737028 | Disulfide exchange folding of insulin-like growth factor I. | 1992 Feb 18 |
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| 33 |
1756863 | A Lys27-to-Glu27 mutation in the human insulin-like growth factor-1 prevents disulfide linked dimerization and allows secretion of BiP when expressed in yeast. | 1991 Dec 9 |
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| 34 |
1888034 | Transpeptidation during the analytical proteolysis of proteins. | 1991 Jul |
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| 35 |
2050146 | Alpha-factor-leader-directed secretion of recombinant human-insulin-like growth factor I from Saccharomyces cerevisiae. Precursor formation and processing in the yeast secretory pathway. | 1991 Jun 15 |
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| 36 |
2201313 | An insulin-like compound consisting of the B-chain of bovine insulin and an A-chain corresponding to a modified A- and the D-domains of human insulin-like growth factor I. | 1990 Apr |
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| 37 |
2611257 | IGF-1-dependent subunit communication of the IGF-1 holoreceptor: interactions between alpha beta heterodimeric receptor halves. | 1989 Dec 12 |
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| 38 |
2628430 | Direct identification of disulfide bond linkages in human insulin-like growth factor I (IGF-I) by chemical synthesis. | 1989 Dec |
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3056519 | Determinants of growth-promoting activity reside in the A-domain of insulin-like growth factor I. | 1988 Aug 9 |
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| 40 |
3884381 | Degradation of somatomedins by the thioredoxin system. | 1985 Apr 8 |
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| 41 |
6572973 | Total synthesis of insulin-like growth factor I (somatomedin C). | 1983 Apr |
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| 42 |
632300 | The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. | 1978 Apr 25 |
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