Pub. Date : 1997 Jun 15
PMID : 9186491
3 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Insulin-like growth factor-I (IGF-I) has three disulfide bonds and refolding of the fully reduced molecule generates varying ratios of correctly (PII) and incorrectly (PI) folded forms via several intermediates. | Disulfides | insulin like growth factor 1 | Homo sapiens | ||
| 2 | Insulin-like growth factor-I (IGF-I) has three disulfide bonds and refolding of the fully reduced molecule generates varying ratios of correctly (PII) and incorrectly (PI) folded forms via several intermediates. | Disulfides | insulin like growth factor 1 | Homo sapiens | ||
| 3 | It was concluded from these results that the intermediate forms of IGF-1 can rapidly reshuffle between different disulfide structures, and that formation of the last disulfide bond is not as favorable a process as the conversion to other intermediates. | Disulfides | insulin like growth factor 1 | Homo sapiens | ||