Pub. Date : 2017 Dec 28
PMID : 29172484
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we report a new method for the total chemical synthesis of IGF-1 analogs, which entails the solid-phase synthesis of two IGF-1 precursor chains that is followed by the CuI-catalyzed azide-alkyne cycloaddition ligation and by biomimetic formation of a native pattern of disulfides. | Disulfides | insulin like growth factor 1 | Homo sapiens |
| 2 | Here, we report a new method for the total chemical synthesis of IGF-1 analogs, which entails the solid-phase synthesis of two IGF-1 precursor chains that is followed by the CuI-catalyzed azide-alkyne cycloaddition ligation and by biomimetic formation of a native pattern of disulfides. | Disulfides | insulin like growth factor 1 | Homo sapiens |
| 3 | These new synthetic IGF-1 analogs are unique examples of disulfide bonds" rich proteins with intra main-chain triazole links. | Disulfides | insulin like growth factor 1 | Homo sapiens |