Iron

tumor protein p53 ; Homo sapiens







70 Article(s)
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Pub. Year
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1 35447365 Role and mechanism of ferroptosis in neurological diseases. 2022 Jul 1
2 35505371 Rho family GTPase 1 (RND1), a novel regulator of p53, enhances ferroptosis in glioblastoma. 2022 May 3 1
3 33073884 Bis(bipyridine)ruthenium(II) Ferrocenyl β-Diketonate Complexes: Exhibiting Nanomolar Potency against Human Cancer Cell Lines. 2021 Feb 19 1
4 33520115 Reversing oncogenic transformation with iron chelation. 2021 Jan 19 1
5 33785447 The complexity of p53-mediated metabolic regulation in tumor suppression. 2021 Mar 27 1
6 33821487 Role of iron and iron-related proteins in mesenchymal stem cells: Cellular and clinical aspects. 2021 Oct 1
7 34004477 Iron-bearing nanoparticles trigger human umbilical vein endothelial cells ferroptotic responses by promoting intracellular iron level. 2021 Oct 15 1
8 34298093 Iron deficiency exacerbates cisplatin- or rhabdomyolysis-induced acute kidney injury through promoting iron-catalyzed oxidative damage. 2021 Sep 1
9 34395447 The p53 Family: A Role in Lipid and Iron Metabolism. 2021 2
10 34502536 Fe-N Co-Doped Titanium Dioxide Nanoparticles Induce Cell Death in Human Lung Fibroblasts in a p53-Independent Manner. 2021 Sep 6 2
11 34831070 Iron Metabolism as a Potential Mechanism for Inducing TRAIL-Mediated Extrinsic Apoptosis Using Methylsulfonylmethane in Embryonic Cancer Stem Cells. 2021 Oct 22 1
12 34888245 High-LET Carbon and Iron Ions Elicit a Prolonged and Amplified p53 Signaling and Inflammatory Response Compared to low-LET X-Rays in Human Peripheral Blood Mononuclear Cells. 2021 1
13 31980600 African-centric TP53 variant increases iron accumulation and bacterial pathogenesis but improves response to malaria toxin. 2020 Jan 24 1
14 32193389 Author Correction: African-centric TP53 variant increases iron accumulation and bacterial pathogenesis but improves response to malaria toxin. 2020 Mar 19 1
15 32718025 The Intersection of DNA Damage Response and Ferroptosis-A Rationale for Combination Therapeutics. 2020 Jul 23 1
16 32863216 The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cells. 2020 Sep 1
17 32942535 Distinct TP53 Mutation Types Exhibit Increased Sensitivity to Ferroptosis Independently of Changes in Iron Regulatory Protein Activity. 2020 Sep 15 7
18 33081324 Deferasirox-Dependent Iron Chelation Enhances Mitochondrial Dysfunction and Restores p53 Signaling by Stabilization of p53 Family Members in Leukemic Cells. 2020 Oct 16 2
19 30133149 p53 tumor suppressor and iron homeostasis. 2019 Feb 1
20 31191795 p53-Mediated PI3K/AKT/mTOR Pathway Played a Role in PtoxDpt-Induced EMT Inhibition in Liver Cancer Cell Lines. 2019 1
21 31500291 Distinct TP53 Mutation Subtypes Differentially Influence Cellular Iron Metabolism. 2019 Sep 7 8
22 29544765 shRNA targeting of ferritin heavy chain activates H19/miR-675 axis in K562 cells. 2018 May 30 1
23 29695998 The p53 Tumor Suppressor in the Control of Metabolism and Ferroptosis. 2018 2
24 29777905 Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes. 2018 Sep 1
25 29872820 The involvement of iron in chemerin induced cell cycle arrest in human hepatic carcinoma SMMC7721 cells. 2018 Jun 20 1
26 30141807 Iron depletion participates in the suppression of cell proliferation induced by lipin1 overexpression. 2018 Sep 19 1
27 28500782 Melatonin protects bone marrow mesenchymal stem cells against iron overload-induced aberrant differentiation and senescence. 2017 Oct 2
28 29292794 The Tumor Suppressor, P53, Decreases the Metal Transporter, ZIP14. 2017 Dec 8 3
29 26517689 Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy. 2016 Jan 12 2
30 27308524 The heme-p53 interaction: Linking iron metabolism to p53 signaling and tumorigenesis. 2016 Jan 2
31 25594146 Fimbrial cells exposure to catalytic iron mimics carcinogenic changes. 2015 Mar 1
32 26560363 Regulation of iron homeostasis by the p53-ISCU pathway. 2015 Nov 12 7
33 24568186 15-deoxy-Δ12,14-prostaglandin J₂ induces p53 expression through Nrf2-mediated upregulation of heme oxygenase-1 in human breast cancer cells. 2014 Sep 3
34 24685134 Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function. 2014 Apr 10 11
35 25158131 p53 directly regulates the transcription of the human frataxin gene and its lack of regulation in tumor cells decreases the utilization of mitochondrial iron. 2014 Nov 1 1
36 25217696 JAK2V617F+ myeloproliferative neoplasm clones evoke paracrine DNA damage to adjacent normal cells through secretion of lipocalin-2. 2014 Nov 6 1
37 23469783 [Effect and mechanism of iron-catalyzed oxidative stress on mesenchymal stem cells]. 2013 Feb 1
38 23483119 Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents. 2013 May 2
39 23772810 Free iron catalyzes oxidative damage to hematopoietic cells/mesenchymal stem cells in vitro and suppresses hematopoiesis in iron overload patients. 2013 Sep 1
40 23946774 Mitigating effects of L-selenomethionine on low-dose iron ion radiation-induced changes in gene expression associated with cellular stress. 2013 Jul 1
41 23983135 Dietary heme iron and the risk of colorectal cancer with specific mutations in KRAS and APC. 2013 Dec 2
42 24112172 Inhibitory effect of iron on in vitro proliferation of smooth muscle cells. 2013 3
43 20019189 Iron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis. 2010 Feb 8
44 20023006 Iron chelator-mediated alterations in gene expression: identification of novel iron-regulated molecules that are molecular targets of hypoxia-inducible factor-1 alpha and p53. 2010 Mar 3
45 20041757 Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions. 2010 Jan 1
46 20185936 Penicillamine as a potent protector against injurious effects of cigarette smoke in aerodigestive tract cancer. 2010 1
47 19716362 Ferritin binds and activates p53 under oxidative stress. 2009 Nov 20 1
48 18042465 Concurrent expression of heme oxygenase-1 and p53 in human retinal pigment epithelial cell line. 2008 Jan 25 2
49 18314014 Biological contexts for DNA charge transport chemistry. 2008 Apr 1
50 18819919 Post-transcriptional modulation of iron homeostasis during p53-dependent growth arrest. 2008 Dec 5 3