Title : The Intersection of DNA Damage Response and Ferroptosis-A Rationale for Combination Therapeutics.

Pub. Date : 2020 Jul 23

PMID : 32718025






1 Functional Relationships(s)
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1 Recently, several studies have identified intricate and complicated interplay between ferroptosis, ionizing radiation (IR), ATM (ataxia-telangiectasia mutated)/ATR (ATM and Rad3-related), and tumor suppressor p53, which signifies the participation of the DNA damage response (DDR) in iron-related cell death. Iron tumor protein p53 Homo sapiens