Etoposide

tumor protein p53 ; Homo sapiens







267 Article(s)
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1 35178190 Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity. 2022 6
2 35217496 DLG2 impairs dsDNA break repair and maintains genome integrity in neuroblastoma. 2022 Apr 1
3 35410287 Single-cell analysis of p53 transitional dynamics unravels stimulus- and cell type-dependent signaling output motifs. 2022 Apr 11 1
4 35421634 BAK plays a key role in A-1331852-induced apoptosis in senescent chondrocytes. 2022 Jun 18 1
5 32786121 The SUMO-specific protease SENP1 deSUMOylates p53 and regulates its activity. 2021 Feb 1
6 33627632 Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane. 2021 Feb 24 1
7 34411980 Structural optimization, synthesis and in vitro synergistic anticancer activities of combinations of new N3-substituted dihydropyrimidine calcium channel blockers with cisplatin and etoposide. 2021 Oct 1
8 31605433 Downregulation of the inflammatory network in senescent fibroblasts and aging tissues of the long-lived and cancer-resistant subterranean wild rodent, Spalax. 2020 Jan 1
9 31940492 FBXW7 Confers Radiation Survival by Targeting p53 for Degradation. 2020 Jan 14 2
10 32098913 β-Actin facilitates etoposide-induced p53 nuclear import. 2020 1
11 32332775 Interleukin-1α associates with the tumor suppressor p53 following DNA damage. 2020 Apr 24 1
12 30144069 Serine/threonine kinase 31 promotes PDCD5-mediated apoptosis in p53-dependent human colon cancer cells. 2019 Mar 2
13 30478995 CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner. 2019 Jul 1
14 30614034 Signaling Crosstalk of FHIT, p53, and p38 in etoposide-induced apoptosis in MCF-7 cells. 2019 Jun 5
15 30784913 Integrated analysis of the prognostic value of TP53 dependent etoposide-induced gene 24 in non-small cell lung cancer. 2019 Apr 2
16 30900772 Distinct mutation spectrum, clinical outcome and therapeutic responses of typical complex/monosomy karyotype acute myeloid leukemia carrying TP53 mutations. 2019 Jun 1
17 30943920 Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells. 2019 Apr 3 1
18 30966857 Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks. 2019 Apr 2
19 31097220 Effect of EI24 expression on the tumorigenesis of ApcMin/+ colorectal cancer mouse model. 2019 Jul 5 1
20 31396480 EI24, as a Component of Autophagy, Is Involved in Pancreatic Cell Proliferation. 2019 1
21 31528096 Growth arrest-specific gene 2 suppresses hepatocarcinogenesis by intervention of cell cycle and p53-dependent apoptosis. 2019 Aug 28 1
22 29030066 Etoposide induced NMI promotes cell apoptosis by activating the ARF-p53 signaling pathway in lung carcinoma. 2018 Jan 1 3
23 29309885 HBXIP regulates etoposide-induced cell cycle checkpoints and apoptosis in MCF-7 human breast carcinoma cells. 2018 Mar 20 1
24 29372665 DNA methylation of the Oct4A enhancers in embryonal carcinoma cells after etoposide treatment is associated with alternative splicing and altered pluripotency in reversibly senescent cells. 2018 2
25 29397400 Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells. 2018 Apr 2
26 29467390 FGF1 induces resistance to chemotherapy in ovarian granulosa tumor cells through regulation of p53 mitochondrial localization. 2018 Feb 21 2
27 29471073 The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells. 2018 Apr 1 4
28 29541168 Etoposide radiosensitizes p53-defective cholangiocarcinoma cell lines independent of their G2 checkpoint efficacies. 2018 Mar 4
29 29653431 Inhibition of NAMPT sensitizes MOLT4 leukemia cells for etoposide treatment through the SIRT2-p53 pathway. 2018 Jun 2
30 30520728 The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage. 2018 Dec 6 1
31 27982581 Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage. 2017 Apr 17 1
32 27993669 Contrasting effects of glutamine deprivation on apoptosis induced by conventionally used anticancer drugs. 2017 Mar 1
33 28051100 Protein serine/threonine phosphatase PPEF-1 suppresses genotoxic stress response via dephosphorylation of PDCD5. 2017 Jan 4 1
34 28081228 Resistance for Genotoxic Damage in Mesenchymal Stromal Cells Is Increased by Hypoxia but Not Generally Dependent on p53-Regulated Cell Cycle Arrest. 2017 1
35 28113103 Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells. 2017 Apr 1
36 28159923 The anti-neoplastic activity of Vandetanib against high-risk medulloblastoma variants is profoundly enhanced by additional PI3K inhibition. 2017 Jul 18 1
37 28195382 Contribution of ATM and ATR kinase pathways to p53-mediated response in etoposide and methyl methanesulfonate induced DNA damage. 2017 Mar 2
38 28196907 Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function. 2017 Feb 14 2
39 28928376 Oligo-Fucoidan prevents IL-6 and CCL2 production and cooperates with p53 to suppress ATM signaling and tumor progression. 2017 Sep 19 4
40 29048426 FGF1 protects neuroblastoma SH-SY5Y cells from p53-dependent apoptosis through an intracrine pathway regulated by FGF1 phosphorylation. 2017 Aug 31 1
41 29137250 Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation. 2017 Oct 10 1
42 26625199 Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1. 2016 Jan 12 2
43 26646449 SIRT1 inhibition impairs non-homologous end joining DNA damage repair by increasing Ku70 acetylation in chronic myeloid leukemia cells. 2016 Mar 22 1
44 26973857 EZH2 inhibition re-sensitizes multidrug resistant B-cell lymphomas to etoposide mediated apoptosis. 2016 2
45 26986476 PTEN enhances G2/M arrest in etoposide-treated MCF‑7 cells through activation of the ATM pathway. 2016 May 1
46 27069137 Long Non-coding RNA, PANDA, Contributes to the Stabilization of p53 Tumor Suppressor Protein. 2016 Apr 1
47 27514406 Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner. 2016 Nov 1
48 27545311 Identification of cellular senescence-specific genes by comparative transcriptomics. 2016 Aug 22 1
49 25088203 BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation. 2015 Jun 4 1
50 25444898 DNAJB1 destabilizes PDCD5 to suppress p53-mediated apoptosis. 2015 Feb 1 1