Etoposide

tumor protein p53 ; Homo sapiens







267 Article(s)
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51 25568206 Impact of the adenoviral E4 Orf3 protein on the activity and posttranslational modification of p53. 2015 Mar 1
52 25750273 The effect of silibinin in enhancing toxicity of temozolomide and etoposide in p53 and PTEN-mutated resistant glioma cell lines. 2015 Mar 1
53 25821946 Rap1 is indispensable for TRF2 function in etoposide-induced DNA damage response in gastric cancer cell line. 2015 Mar 30 1
54 25866679 Caspase Activation and Aberrant Cell Growth in a p53(+/+) Cell Line from a Li-Fraumeni Syndrome Family. 2015 2
55 25954860 Low expression of phosphatase and tensin homolog in clear‑cell renal cell carcinoma contributes to chemoresistance through activating the Akt/HDM2 signaling pathway. 2015 Aug 3
56 25964101 Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells. 2015 Aug 1
57 26070487 5-Lipoxygenase is a direct p53 target gene in humans. 2015 Aug 2
58 26077467 Programmed cell death 5 mediates HDAC3 decay to promote genotoxic stress response. 2015 Jun 16 4
59 26102294 Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide. 2015 2
60 26158294 p53 directly activates cystatin D/CST5 to mediate mesenchymal-epithelial transition: a possible link to tumor suppression by vitamin D3. 2015 Jun 30 1
61 26259609 Etoposide Induces Necrosis Through p53-Mediated Antiapoptosis in Human Kidney Proximal Tubule Cells. 2015 Nov 2
62 23318437 Knockdown of RNF2 induces apoptosis by regulating MDM2 and p53 stability. 2014 Jan 23 1
63 24056736 Extensive post-translational modification of active and inactivated forms of endogenous p53. 2014 Jan 2
64 24486906 A plausible model for bimodal p53 switch in DNA damage response. 2014 Mar 3 2
65 24626184 The RNA helicase/transcriptional co-regulator, p68 (DDX5), stimulates expression of oncogenic protein kinase, Polo-like kinase-1 (PLK1), and is associated with elevated PLK1 levels in human breast cancers. 2014 1
66 24732641 MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients. 2014 1
67 24743655 Transcriptomes and shRNA suppressors in a TP53 allele-specific model of early-onset colon cancer in African Americans. 2014 Jul 2
68 24786831 Proline, glutamic acid and leucine-rich protein-1 is essential for optimal p53-mediated DNA damage response. 2014 Sep 1
69 25250818 Mir-34a mimics are potential therapeutic agents for p53-mutated and chemo-resistant brain tumour cells. 2014 1
70 25490093 p53-dependent activation of microRNA-34a in response to etoposide-induced DNA damage in osteosarcoma cell lines not impaired by dominant negative p53 expression. 2014 7
71 22469985 Kaposi's sarcoma herpesvirus lytic replication compromises apoptotic response to p53 reactivation in virus-induced lymphomas. 2013 Feb 28 1
72 23054612 Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53. 2013 Jan 1
73 23150668 Polycomb group protein PHF1 regulates p53-dependent cell growth arrest and apoptosis. 2013 Jan 4 1
74 23161404 Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y cells. 2013 Mar 3
75 23287532 DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells. 2013 Feb 1 1
76 23382381 Supervillin-mediated suppression of p53 protein enhances cell survival. 2013 Mar 15 1
77 23474493 CBX8 suppresses Sirtinol-induced premature senescence in human breast cancer cells via cooperation with SIRT1. 2013 Jul 28 1
78 23690541 Intervention in genotoxic stress-induced senescence by cordycepin through activation of eIF2α and suppression of Sp1. 2013 Aug 1
79 23835407 miR-375 targets the p53 gene to regulate cellular response to ionizing radiation and etoposide in gastric cancer cells. 2013 Sep 2
80 23954287 E2F1 activates p53 transcription through its distal site and participates in apoptosis induction in HPV-positive cells. 2013 Oct 1 1
81 24055188 Synergistic anti-proliferative effect of resveratrol and etoposide on human hepatocellular and colon cancer cell lines. 2013 Oct 15 4
82 22200537 Liposomal formulations of Etoposide and Docetaxel for p53 mediated enhanced cytotoxicity in lung cancer cell lines. 2012 Mar 2
83 22508727 Mutant p53 cooperates with ETS2 to promote etoposide resistance. 2012 Apr 15 1
84 22511763 TATA-binding protein (TBP)-like protein is required for p53-dependent transcriptional activation of upstream promoter of p21Waf1/Cip1 gene. 2012 Jun 8 1
85 22739265 Functional switching of ATM: sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells. 2012 Aug 1
86 22763759 Loss of TP53 expression in immortalized choroid plexus epithelial cells results in increased resistance to anticancer agents. 2012 Sep 1
87 22830357 The over-expression of miR-34a fails to block DoHH2 lymphoma cell proliferation by reducing p53 via c-MYC down-regulation. 2012 Aug 1
88 22904680 The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform. 2012 Jul 2
89 22948151 Identification of HEXIM1 as a positive regulator of p53. 2012 Oct 19 1
90 23058634 Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells. 2012 Nov 1 1
91 23272236 Sensitive detection and monitoring of senescence-associated secretory phenotype by SASP-RAP assay. 2012 1
92 20931131 Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology. 2011 Jan 3
93 21274505 Autophagy inhibition enhances etoposide-induced cell death in human hepatoma G2 cells. 2011 Apr 1
94 21386980 Downregulation of VRK1 by p53 in response to DNA damage is mediated by the autophagic pathway. 2011 Feb 28 2
95 21394211 Role of p53 serine 46 in p53 target gene regulation. 2011 Mar 4 1
96 21441950 Anthracyclines induce the accumulation of mutant p53 through E2F1-dependent and -independent mechanisms. 2011 Aug 18 1
97 21468663 Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment. 2011 Jul 3
98 21552291 p53 promotes cellular survival in a context-dependent manner by directly inducing the expression of haeme-oxygenase-1. 2011 Nov 3 1
99 21554433 Insulin but not leptin protects olfactory mucosa from apoptosis. 2011 Jul 1
100 21565980 Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network. 2011 Jul 1 1