Pub. Date : 2016
PMID : 26973857
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The tumor suppressor, p53 is central for apoptotic response to multiple DNA damaging agents used to treat aggressive B-cell lymphomas, including etoposide. | Etoposide | tumor protein p53 | Homo sapiens |
2 | Using B-cell lymphoma cell lines resistant to etoposide induced cell death; we show that p53 is dramatically down regulated and MDMX, a negative regulator of p53, is significantly up regulated. | Etoposide | tumor protein p53 | Homo sapiens |