Ascorbic Acid

tumor protein p53 ; Homo sapiens







32 Article(s)
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1 32008465 Vitamin C supplementation had no side effect in non-cancer, but had anticancer properties in ovarian cancer cells. 2021 Jun 1
2 33297189 Functional benefit and molecular mechanism of vitamin C against perfluorooctanesulfonate-associated leukemia. 2021 Jan 1
3 33580460 Role of p53 in transcriptional repression of SVCT2. 2021 Feb 1
4 34497762 Ascorbate Inhibits Proliferation and Promotes Myeloid Differentiation in TP53-Mutant Leukemia. 2021 2
5 31388677 p53 activation by Cr(VI): a transcriptionally limited response induced by ATR kinase in S-phase. 2019 Aug 6 4
6 27231022 Vitamin C promotes the proliferation of human adipose-derived stem cells via p53-p21 pathway. 2016 Jul 2 3
7 27236003 Honokiol induces autophagic cell death in malignant glioma through reactive oxygen species-mediated regulation of the p53/PI3K/Akt/mTOR signaling pathway. 2016 Aug 1 2
8 27339904 Combined treatment with vitamin C and sulindac synergistically induces p53- and ROS-dependent apoptosis in human colon cancer cells. 2016 Sep 6 2
9 27613187 Vitamin C in synergism with cisplatin induces cell death in cervical cancer cells through altered redox cycling and p53 upregulation. 2016 Dec 1
10 25586269 SIAH1-induced p34SEI-1 polyubiquitination/degradation mediates p53 preferential vitamin C cytotoxicity. 2015 Mar 3
11 25839657 Endogenous ROS levels are increased in replicative senescence in human bone marrow mesenchymal stromal cells. 2015 May 15 1
12 25958121 Relief of delayed oxidative stress by ascorbic acid can suppress radiation-induced cellular senescence in mammalian fibroblast cells. 2015 Mar 1
13 25147862 Vitamin C protected human retinal pigmented epithelium from oxidant injury depending on regulating SIRT1. 2014 2
14 22892142 Enhanced antitumor activity of vitamin C via p53 in cancer cells. 2012 Oct 15 13
15 21429301 Vitamin C increases the apoptosis via up-regulation p53 during cisplatin treatment in human colon cancer cells. 2011 Mar 1
16 21663679 Vitamin K3 and vitamin C alone or in combination induced apoptosis in leukemia cells by a similar oxidative stress signalling mechanism. 2011 Jun 10 1
17 20067818 Cellular and molecular mechanisms of bromate-induced cytotoxicity in human and rat kidney cells. 2010 Feb 28 1
18 20085733 Powering reprogramming with vitamin C. 2010 Jan 8 1
19 19744477 Emodin induces a reactive oxygen species-dependent and ATM-p53-Bax mediated cytotoxicity in lung cancer cells. 2009 Nov 25 1
20 18720420 Extracellular dopamine induces the oxidative toxicity of SH-SY5Y cells. 2008 Nov 1
21 18949386 Vitamin C inhibits p53-induced replicative senescence through suppression of ROS production and p38 MAPK activity. 2008 Nov 4
22 17301063 Cellular vitamin C increases chromate toxicity via a death program requiring mismatch repair but not p53. 2007 Jul 1
23 17352246 Ascorbic acid induces apoptosis in adult T-cell leukemia. 2007 Jan-Feb 1
24 20535395 Ascorbic acid extends replicative life span of human embryonic fibroblast by reducing DNA and mitochondrial damages. 2007 Summer 4
25 17119452 Sodium ascorbate inhibits growth via the induction of cell cycle arrest and apoptosis in human malignant melanoma A375.S2 cells. 2006 Dec 2
26 15887239 Vitamin C transiently arrests cancer cell cycle progression in S phase and G2/M boundary by modulating the kinetics of activation and the subcellular localization of Cdc25C phosphatase. 2005 Nov 1
27 15904897 Reactive oxygen species-mediated induction of apoptosis by a plant alkaloid 6-methoxydihydrosanguinarine in HepG2 cells. 2005 Jul 15 1
28 15905035 Coenzyme Q2 induced p53-dependent apoptosis. 2005 Jun 20 1
29 12823592 Liver p53 expression in patients with HCV-related chronic hepatitis. 2003 Jul 1
30 12023887 Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage. 2002 Jun 1 1
31 11401473 Vitamin C augments chemotherapeutic response of cervical carcinoma HeLa cells by stabilizing P53. 2001 Mar 30 3
32 9257692 Active oxygen species mediate the solar ultraviolet radiation-dependent increase in the tumour suppressor protein p53 in human skin fibroblasts. 1997 Jul 21 1