Title : Reactive oxygen species-mediated induction of apoptosis by a plant alkaloid 6-methoxydihydrosanguinarine in HepG2 cells.

Pub. Date : 2005 Jul 15

PMID : 15904897






1 Functional Relationships(s)
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1 Our results also show that preincubation of HepG2 cells with vitamin C decreased the expression of p53 and bax and inhibited the release of cytochrome c, activation of downstream caspase and the cleavage of poly(ADP-ribose) polymerase, thus inhibiting the apoptosis inducing effect of 6ME. Ascorbic Acid tumor protein p53 Homo sapiens