trichostatin A

tumor protein p53 ; Homo sapiens







91 Article(s)
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1 30318011 Combination Treatment of p53-Null HL-60 cells with Histone Deacetylase Inhibitors and Chlorambucil Augments Apoptosis and Increases BCL6 and p21 Gene Expression. 2019 1
2 30655814 Trichostatin A induces p53-dependent endoplasmic reticulum stress in human colon cancer cells. 2019 Jan 3
3 30958996 Quercetin enhances the antitumor activity of trichostatin A through up-regulation of p300 protein expression in p53 null cancer cells. 2019 Jun 1 1
4 28884479 Transcriptional repression of Aurora-A gene by wild-type p53 through directly binding to its promoter with histone deacetylase 1 and mSin3a. 2018 Jan 1 2
5 29233643 Trichostatin A inhibits deacetylation of histone H3 and p53 by SIRT6. 2018 Jan 15 1
6 29735783 Antiproliferative Effects of Epigenetic Modifier Drugs Through E-cadherin Up-regulation in Liver Cancer Cell Lines. 2018 May-June 1
7 28160167 Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells. 2017 Apr 1
8 25409339 Treatment of buffalo (Bubalus bubalis) donor cells with trichostatin A and 5-aza-2'-deoxycytidine alters their growth characteristics, gene expression and epigenetic status and improves the in vitro developmental competence, quality and epigenetic status of cloned embryos. 2016 Apr 1
9 26768552 The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferase. 2016 Feb 1 3
10 27716272 The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. 2016 Sep 30 1
11 27877082 Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation. 2016 2
12 27934110 Molecular Imaging Biosensor Monitors p53 Sumoylation in Cells and Living Mice. 2016 Dec 6 1
13 25515622 Trichostatin A modulates intracellular reactive oxygen species through SOD2 and FOXO1 in human bone marrow-mesenchymal stem cells. 2015 Jan 1
14 24676336 Breast cancer cells are arrested at different phases of the cell cycle following the re-expression of ARHI. 2014 May 1
15 25036040 Integrating genomics and proteomics data to predict drug effects using binary linear programming. 2014 1
16 22290509 Curcumin enhances the anticancer effects of trichostatin a in breast cancer cells. 2013 May 1
17 23342112 Quercetin enhances the antitumor activity of trichostatin A through upregulation of p53 protein expression in vitro and in vivo. 2013 4
18 23474493 CBX8 suppresses Sirtinol-induced premature senescence in human breast cancer cells via cooperation with SIRT1. 2013 Jul 28 1
19 23745024 Mechanisms of trichostatin A inhibiting AGS proliferation and identification of lysine-acetylated proteins. 2013 Jun 7 2
20 23758695 The effects of a histone deacetylase inhibitor on biological behavior of diffuse large B-cell lymphoma cell lines and insights into the underlying mechanisms. 2013 Jun 7 1
21 22214764 Interaction between ZBP-89 and p53 mutants and its contribution to effects of HDACi on hepatocellular carcinoma. 2012 Jan 15 1
22 22270849 P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells. 2012 May 4
23 22493143 Synergistic effect of p53 on TSA-induced stanniocalcin 1 expression in human nasopharyngeal carcinoma cells, CNE2. 2012 Jun 5
24 22552631 The histone deacetylase inhibitor trichostatin A induces cell cycle arrest and apoptosis in colorectal cancer cells via p53-dependent and -independent pathways. 2012 Jul 7
25 23359343 Inhibitory Effects of 5-Aza-2'-Deoxycytidine and Trichostatin A in Combination with p53-Expressing Adenovirus on Human Laryngocarcinoma Cells. 2012 Sep 3
26 20931131 Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology. 2011 Jan 1
27 21346816 Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis. 2011 Feb 8 1
28 21376104 p53 in trichostatin A induced C6 glioma cell death. 2011 May 5
29 21380726 Different effect of protein kinase B/Akt and extracellular signal-regulated kinase inhibition on trichostatin A-induced apoptosis in epithelial ovarian carcinoma cell lines. 2011 Jul 1
30 21468663 Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment. 2011 Jul 3
31 21519790 Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. 2011 Jul 2
32 19889954 Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells. 2010 Feb 1
33 20375332 C-terminal cleavage of DeltaNp63alpha is associated with TSA-induced apoptosis in immortalized corneal epithelial cells. 2010 Aug 1
34 20505264 HDAC inhibitor-mediated radiosensitization in human carcinoma cells: a general phenomenon? 2010 1
35 20640432 Differential expression of p53 and p504s in hyperplastic polyp, sessile serrated adenoma and traditional serrated adenoma. 2010 Oct 1
36 20681406 The inhibitor of growth 1 (ING1) is involved in trichostatin A-induced apoptosis and caspase 3 signaling in p53-deficient glioblastoma cells. 2010 1
37 20811720 Biological effects of induced MYCN hyper-expression in MYCN-amplified neuroblastomas. 2010 Oct 3
38 20868669 18β-Glycyrrhetinic acid potentiates apoptotic effect of trichostatin A on human epithelial ovarian carcinoma cell lines. 2010 Dec 15 1
39 20962589 p53-dependent repression of polo-like kinase-1 (PLK1). 2010 Oct 15 1
40 19513516 Trichostatin A with adenovirus-mediated p53 gene transfer synergistically induces apoptosis in breast cancer cell line MDA-MB-231. 2009 Jul 1
41 18097557 Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. 2008 Jan 2
42 18419600 Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis. 2008 Apr 1
43 18483381 Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death. 2008 May 15 1
44 18566213 Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells. 2008 Jun 1
45 18644983 Modulation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by Zac1 through the antagonistic regulators p53 and histone deacetylase 1 in HeLa Cells. 2008 Jul 1
46 18645003 Array-based analysis of the effects of trichostatin A and CG-1521 on cell cycle and cell death in LNCaP prostate cancer cells. 2008 Jul 2
47 18708766 Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer. 2008 Sep 1
48 18949380 Effects of trichostatin A, a histone deacetylase inhibitor, on the regulation of apoptosis in H-ras-transformed breast epithelial cells. 2008 Nov 1
49 17121856 Site-specific acetylation of p53 directs selective transcription complex assembly. 2007 Feb 16 2
50 17172643 Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing. 2007 Feb 16 2