Pub. Date : 2011 May
PMID : 21376104
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p53 in trichostatin A induced C6 glioma cell death. | trichostatin A | tumor protein p53 | Homo sapiens |
| 2 | RESULTS: TSA activated p38 mitogen-activated protein kinase (p38MAPK), leading to p53 phosphorylation and activation. | trichostatin A | tumor protein p53 | Homo sapiens |
| 3 | CONCLUSIONS: TSA may cause C6 cell apoptosis through activating p38MAPK-p53 cascade resulting in Bax expression and survivin suppression. | trichostatin A | tumor protein p53 | Homo sapiens |
| 4 | GENERAL SIGNIFICANCE: TSA-induced p53 activation may occur through p53 modification by phosphorylation or by acetylation via IKK inactivation. | trichostatin A | tumor protein p53 | Homo sapiens |
| 5 | GENERAL SIGNIFICANCE: TSA-induced p53 activation may occur through p53 modification by phosphorylation or by acetylation via IKK inactivation. | trichostatin A | tumor protein p53 | Homo sapiens |