Title : The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferase.

Pub. Date : 2016 Feb 1

PMID : 26768552






3 Functional Relationships(s)
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Protein Name
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1 The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferase. trichostatin A tumor protein p53 Homo sapiens
2 The inhibitor of acetyltransferase, anacardic acid, diminished the enhancing effect of genistein on all TSA-induced histone/p53 acetylation and apoptosis. trichostatin A tumor protein p53 Homo sapiens
3 Taken together, these results suggest that the enhancing effects of genistein on TSA-induced apoptosis in lung cancer cells were p53-dependent and were associated with histone/non-histone protein acetylation. trichostatin A tumor protein p53 Homo sapiens