Pub. Date : 2016 Feb 1
PMID : 26768552
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferase. | trichostatin A | tumor protein p53 | Homo sapiens |
2 | The inhibitor of acetyltransferase, anacardic acid, diminished the enhancing effect of genistein on all TSA-induced histone/p53 acetylation and apoptosis. | trichostatin A | tumor protein p53 | Homo sapiens |
3 | Taken together, these results suggest that the enhancing effects of genistein on TSA-induced apoptosis in lung cancer cells were p53-dependent and were associated with histone/non-histone protein acetylation. | trichostatin A | tumor protein p53 | Homo sapiens |