Ceramides

insulin ; Homo sapiens







222 Article(s)
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101 24214972 Ceramides and glucosylceramides are independent antagonists of insulin signaling. 2014 Jan 10 4
102 24606127 Adiponectin inhibits insulin function in primary trophoblasts by PPARα-mediated ceramide synthesis. 2014 Apr 2
103 24650522 Ceramide inhibits insulin-stimulated Akt phosphorylation through activation of Rheb/mTORC1/S6K signaling in skeletal muscle. 2014 Jul 2
104 24705014 Dynamic GLUT4 sorting through a syntaxin-6 compartment in muscle cells is derailed by insulin resistance-causing ceramide. 2014 Apr 4 2
105 24749054 On ceramides, other sphingolipids and impaired glucose homeostasis. 2014 Jun 4
106 24892004 Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress. 2014 1
107 24936246 Defect of insulin signal in peripheral tissues: Important role of ceramide. 2014 Jun 15 7
108 24977487 Divergent role of sphingosine 1-phosphate on insulin resistance. 2014 2
109 25058613 Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: a mechanistic insight. 2014 5
110 25126394 Effects of exercise training on mitochondrial function in patients with type 2 diabetes. 2014 Aug 15 1
111 25295788 Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. 2014 Oct 7 1
112 23139352 Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance. 2013 Feb 3
113 23250746 Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages. 2013 Feb 1 1
114 23305978 Adiponectin concentration is associated with muscle insulin sensitivity, AMPK phosphorylation, and ceramide content in skeletal muscles of men but not women. 2013 Mar 1 1
115 23386653 No difference in glycosphingolipid metabolism and mitochondrial function in glucocorticoid-induced insulin resistance in healthy men. 2013 Mar 1
116 23393182 Enhanced skeletal muscle lipid oxidative efficiency in insulin-resistant vs insulin-sensitive nondiabetic, nonobese humans. 2013 Apr 2
117 23529132 Effect of a sustained reduction in plasma free fatty acid concentration on insulin signalling and inflammation in skeletal muscle from human subjects. 2013 Jun 1 1
118 23612696 Plasma ceramides are elevated in female children and adolescents with type 2 diabetes. 2013 2
119 23640727 The effect of short-term overfeeding on serum lipids in healthy humans. 2013 Dec 1
120 23640896 Rac-1 superactivation triggers insulin-independent glucose transporter 4 (GLUT4) translocation that bypasses signaling defects exerted by c-Jun N-terminal kinase (JNK)- and ceramide-induced insulin resistance. 2013 Jun 14 3
121 23835113 Role of ceramide in diabetes mellitus: evidence and mechanisms. 2013 Jul 8 6
122 23896361 Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: impact on small HDL particles. 2013 Nov 1
123 23988586 Dynamics of skeletal muscle lipid pools. 2013 Dec 1
124 23989724 Ceramide accumulation in L6 skeletal muscle cells due to increased activity of ceramide synthase isoforms has opposing effects on insulin action to those caused by palmitate treatment. 2013 Dec 3
125 24269881 Metformin limits ceramide-induced senescence in C2C12 myoblasts. 2013 Nov-Dec 2
126 24376889 Effects of inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate induced insulin resistance in L6 myotubes. 2013 1
127 28664064 Exercise and obesity-induced insulin resistance in skeletal muscle. 2013 Dec 1
128 21437908 Ceramide metabolism is affected by obesity and diabetes in human adipose tissue. 2012 Feb 1
129 22120643 Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity. 2012 Jan 1
130 22176347 High fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism. 2012 Apr 3
131 22297646 Dysfunctional pro-ceramide, ER stress, and insulin/IGF signaling networks with progression of Alzheimer's disease. 2012 1
132 22320914 Alcohol, insulin resistance and the liver-brain axis. 2012 Mar 2
133 22337830 Triangulated mal-signaling in Alzheimer's disease: roles of neurotoxic ceramides, ER stress, and insulin resistance reviewed. 2012 4
134 22385956 Mechanisms for insulin resistance: common threads and missing links. 2012 Mar 2 1
135 22425588 Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects. 2012 Jun 1
136 22560211 A ceramide-centric view of insulin resistance. 2012 May 2 3
137 22577490 Insulin resistance, ceramide accumulation, and endoplasmic reticulum stress in human chronic alcohol-related liver disease. 2012 1
138 22586279 Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure. 2012 Jun 12 1
139 22677645 Sphingolipid content of human adipose tissue: relationship to adiponectin and insulin resistance. 2012 Dec 2
140 22801434 Metabolic derangements mediate cognitive impairment and Alzheimer's disease: role of peripheral insulin-resistance diseases. 2012 Sep 3
141 23054552 Increased bioactive lipids content in human subcutaneous and epicardial fat tissue correlates with insulin resistance. 2012 Dec 1
142 26052434 High-fat load: mechanism(s) of insulin resistance in skeletal muscle. 2012 Dec 1
143 20561942 The twists and turns of sphingolipid pathway in glucose regulation. 2011 Jan 1
144 21176778 Protein kinase C isoforms: mediators of reactive lipid metabolites in the development of insulin resistance. 2011 Jan 21 1
145 21327867 Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide. 2011 May 1
146 21336841 Obesity-associated insulin resistance in skeletal muscle: role of lipid accumulation and physical inactivity. 2011 Sep 2
147 21431854 Why does NAFLD predict type 2 diabetes? 2011 Jun 1
148 21546935 Gastric bypass surgery reduces plasma ceramide subspecies and improves insulin sensitivity in severely obese patients. 2011 Nov 2
149 21570480 Insulin-stimulated glucose uptake and pathways regulating energy metabolism in skeletal muscle cells: the effects of subcutaneous and visceral fat, and long-chain saturated, n-3 and n-6 polyunsaturated fatty acids. 2011 Jul-Aug 2
150 21635197 Ceramide formation as a target in beta-cell survival and function. 2011 Sep 2