Pub. Date : 2011 Sep
PMID : 21635197
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ceramide contributes to endoplasmatic reticulum (ER) stress, decreased mitochondrial membrane potential in insulin-secreting cells and mitochondrial release of cytochrome c into the cytosol, which are all triggers of apoptotic cell death. | Ceramides | insulin | Homo sapiens |
| 2 | Ceramide reduces the activity of voltage gated potassium (Kv)-channels in insulin-secreting cells. | Ceramides | insulin | Homo sapiens |