Palmitic Acid

insulin ; Homo sapiens







121 Article(s)
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51 29223854 Baicalein improves liver inflammation in diabetic db/db mice by regulating HMGB1/TLR4/NF-κB signaling pathway. 2018 Feb 1
52 29290500 Palmitic and Oleic Acid: The Yin and Yang of Fatty Acids in Type 2 Diabetes Mellitus. 2018 Mar 1
53 29311680 Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy. 2018 Jan 8 4
54 29554661 Alkannin Inhibited Hepatic Inflammation in Diabetic Db/Db Mice. 2018 1
55 29667734 Celastrol reverses palmitic acid (PA)-caused TLR4-MD2 activation-dependent insulin resistance via disrupting MD2-related cellular binding to PA. 2018 Oct 5
56 29768267 Type 2 Diabetes Promotes Cell Centrosome Amplification via AKT-ROS-Dependent Signalling of ROCK1 and 14-3-3σ. 2018 1
57 29923306 Acid Sphingomyelinase Down-regulation Alleviates Vascular Endothelial Insulin Resistance in Diabetic Rats. 2018 Dec 1
58 30109329 Microfluidic-enabled quantitative measurements of insulin release dynamics from single islets of Langerhans in response to 5-palmitic acid hydroxy stearic acid. 2018 Sep 11 1
59 30572687 Theaflavins Improve Insulin Sensitivity through Regulating Mitochondrial Biosynthesis in Palmitic Acid-Induced HepG2 Cells. 2018 Dec 19 2
60 28011403 Cyanidin-3-O-glucoside ameliorates palmitate-induced insulin resistance by modulating IRS-1 phosphorylation and release of endothelial derived vasoactive factors. 2017 Mar 4
61 28304381 TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance. 2017 Mar 17 2
62 28656239 Erythropoietin ameliorates PA-induced insulin resistance through the IRS/AKT/FOXO1 and GSK-3β signaling pathway, and inhibits the inflammatory response in HepG2 cells. 2017 Aug 1
63 28827061 Disruption of the mitochondria-associated ER membrane (MAM) plays a central role in palmitic acid-induced insulin resistance. 2017 Oct 1 4
64 28919254 Palmitic acid stimulates energy metabolism and inhibits insulin/PI3K/AKT signaling in differentiated human neuroblastoma cells: The role of mTOR activation and mitochondrial ROS production. 2017 Nov 6
65 28980863 Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-βH1 cells. 2017 Aug 1
66 26475209 Palmitic acid but not palmitoleic acid induces insulin resistance in a human endothelial cell line by decreasing SERCA pump expression. 2016 Jan 8
67 26748475 PGC-1β suppresses saturated fatty acid-induced macrophage inflammation by inhibiting TAK1 activation. 2016 Feb 1
68 26763130 Fructose and glucose combined with free fatty acids induce metabolic disorders in HepG2 cell: A new model to study the impacts of high-fructose/sucrose and high-fat diets in vitro. 2016 Apr 1
69 26982448 Fatty Acid Content of Plasma Triglycerides May Contribute to the Heterogeneity in the Relationship Between Abdominal Obesity and the Metabolic Syndrome. 2016 Aug 2
70 27117849 Capric Acid Up-Regulates UCP3 Expression without PDK4 Induction in Mouse C2C12 Myotubes. 2016 1
71 27250532 Withaferin A protects against palmitic acid-induced endothelial insulin resistance and dysfunction through suppression of oxidative stress and inflammation. 2016 Jun 2 2
72 27255710 Short Term Palmitate Supply Impairs Intestinal Insulin Signaling via Ceramide Production. 2016 Jul 29 4
73 27580020 Mulberry anthocyanin extract ameliorates insulin resistance by regulating PI3K/AKT pathway in HepG2 cells and db/db mice. 2016 Oct 1
74 27639126 Adiponectin protects palmitic acid induced endothelial inflammation and insulin resistance via regulating ROS/IKKβ pathways. 2016 Dec 1
75 25527759 Prospective association of fatty acids in the de novo lipogenesis pathway with risk of type 2 diabetes: the Cardiovascular Health Study. 2015 Jan 1
76 25529328 Silencing miR-106b improves palmitic acid-induced mitochondrial dysfunction and insulin resistance in skeletal myocytes. 2015 May 2
77 25700627 Targeted metabolomic analysis reveals the association between the postprandial change in palmitic acid, branched-chain amino acids and insulin resistance in young obese subjects. 2015 Apr 2
78 25737480 Loss of Egr-1 sensitizes pancreatic β-cells to palmitate-induced ER stress and apoptosis. 2015 Jul 1
79 25815690 Resveratrol analog piceatannol restores the palmitic acid-induced impairment of insulin signaling and production of endothelial nitric oxide via activation of anti-inflammatory and antioxidative heme oxygenase-1 in human endothelial cells. 2015 Jul 3
80 25846498 Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection. 2015 Jun 4
81 25891779 Metformin attenuates palmitic acid-induced insulin resistance in L6 cells through the AMP-activated protein kinase/sterol regulatory element-binding protein-1c pathway. 2015 Jun 2
82 26064210 SHIP2 on pI3K/Akt pathway in palmitic acid stimulated islet β cell. 2015 1
83 26080825 [Effects of conditioned media for rat bone marrow-derived mesenchymal stem cells on palmitic acid-induced insulin resistance in HepG2 cells]. 2015 May 5
84 24384240 Comparison of plasma and erythrocyte membrane fatty acid compositions in patients with end-stage renal disease and type 2 diabetes mellitus. 2014 Feb 1
85 24667753 Palmitic acid in the sn-2 position decreases glucose-dependent insulinotropic polypeptide secretion in healthy adults. 2014 May 1
86 24973767 Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated skeletal muscle insulin resistance. 2014 Aug 5 1
87 25052227 Palmitic acid in the sn-2 position of dietary triacylglycerols does not affect insulin secretion or glucose homeostasis in healthy men and women. 2014 Sep 1
88 25310908 Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway. 2014 Dec 15 1
89 25980295 [The basis principles of primary prevention of atherosclerosis]. 2014 1
90 22966071 Sterol regulatory element-binding protein-1c mediates increase of postprandial stearic acid, a potential target for improving insulin resistance, in hyperlipidemia. 2013 Feb 2
91 21437903 Activation of survival and apoptotic signaling pathways in lymphocytes exposed to palmitic acid. 2012 Jan 1
92 22252473 Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes. 2012 Apr 1
93 22282245 Reduction of insulin resistance in HepG2 cells by knockdown of LITAF expression in human THP-1 macrophages. 2012 Feb 1
94 22624461 [The function of mitochondrion, carnitine, coenzyme-A, fat acids, glucose, the Randle cycle and insulin: a lecture]. 2012 Feb 1
95 22791168 Homoplantaginin modulates insulin sensitivity in endothelial cells by inhibiting inflammation. 2012 3
96 23046938 [Effect of total flavonoids of tartary buckwheat on palmitic acid-induced NO synthesis in EA.hy926 cells]. 2012 Oct 1
97 21194385 Cortical neurons develop insulin resistance and blunted Akt signaling: a potential mechanism contributing to enhanced ischemic injury in diabetes. 2011 May 15 1
98 21505982 Genistein reverses free fatty acid-induced insulin resistance in HepG2 hepatocytes through targeting JNK. 2011 Apr 2
99 21506380 [Prevention of atherosclerosis. Excess of palmitic acid in food--a cause of hypercholesterolemia, inflammatory syndrome, insulin resistance in myocytes, and apoptosis]. 2011 Feb 1
100 21570480 Insulin-stimulated glucose uptake and pathways regulating energy metabolism in skeletal muscle cells: the effects of subcutaneous and visceral fat, and long-chain saturated, n-3 and n-6 polyunsaturated fatty acids. 2011 Jul-Aug 4