Title : Silencing miR-106b improves palmitic acid-induced mitochondrial dysfunction and insulin resistance in skeletal myocytes.

Pub. Date : 2015 May

PMID : 25529328






2 Functional Relationships(s)
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1 In addition, miR-106b negatively regulated skeletal muscle mitochondrial function and insulin sensitivity under PA-induced insulin resistance by targeting Mfn2, which may be associated with reduced ROS and upregulation of the ERR-alpha/PGC-1alpha/Mfn2 axis. Palmitic Acid insulin Homo sapiens
2 In addition, miR-106b negatively regulated skeletal muscle mitochondrial function and insulin sensitivity under PA-induced insulin resistance by targeting Mfn2, which may be associated with reduced ROS and upregulation of the ERR-alpha/PGC-1alpha/Mfn2 axis. Palmitic Acid insulin Homo sapiens