| 1 |
34632715 | Targeting mitochondrial respiration and the BCL2 family in high-grade MYC-associated B-cell lymphoma. | 2022 Mar |
1 |
| 2 |
34728569 | Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas. | 2022 Jan |
1 |
| 3 |
34767916 | Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance. | 2022 Jan |
1 |
| 4 |
35393436 | MEK and MCL-1 sequential inhibition synergize to enhance rhabdomyosarcoma treatment. | 2022 Apr 7 |
1 |
| 5 |
32990536 | Peptide and Small Molecule Inhibitors Targeting Myeloid Cell Leukemia 1 (Mcl-1) as Novel Antitumor Agents. | 2021 |
1 |
| 6 |
33540760 | BMI1-Inhibitor PTC596 in Combination with MCL1 Inhibitor S63845 or MEK Inhibitor Trametinib in the Treatment of Acute Leukemia. | 2021 Feb 2 |
2 |
| 7 |
33564073 | MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma. | 2021 Mar |
1 |
| 8 |
33690800 | Cytokine-like protein 1-induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML. | 2021 Jun 17 |
1 |
| 9 |
34103421 | Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics. | 2021 Jun 8 |
1 |
| 10 |
34331013 | Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss. | 2021 Sep |
1 |
| 11 |
34385422 | Constitutive BAK/MCL1 complexes predict paclitaxel and S63845 sensitivity of ovarian cancer. | 2021 Aug 12 |
3 |
| 12 |
34564697 | Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells. | 2021 Sep 25 |
1 |
| 13 |
34568318 | MCL-1 Inhibition Overcomes Anti-apoptotic Adaptation to Targeted Therapies in B-Cell Precursor Acute Lymphoblastic Leukemia. | 2021 |
1 |
| 14 |
34675185 | Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells. | 2021 Oct 21 |
1 |
| 15 |
34707185 | CD157 signaling promotes survival of acute myeloid leukemia cells and modulates sensitivity to cytarabine through regulation of anti-apoptotic Mcl-1. | 2021 Oct 27 |
2 |
| 16 |
32066201 | Venetoclax, bortezomib and S63845, an MCL1 inhibitor, in multiple myeloma. | 2020 May |
1 |
| 17 |
32346617 | Co-inhibition of BCL-XL and MCL-1 with selective BCL-2 family inhibitors enhances cytotoxicity of cervical cancer cell lines. | 2020 Jul |
1 |
| 18 |
32513939 | MCL1 inhibitors S63845/MIK665 plus Navitoclax synergistically kill difficult-to-treat melanoma cells. | 2020 Jun 8 |
1 |
| 19 |
32659848 | Pairing MCL-1 inhibition with venetoclax improves therapeutic efficiency of BH3-mimetics in AML. | 2020 Nov |
1 |
| 20 |
32724460 | Mcl-1 inhibition overcomes intrinsic and acquired regorafenib resistance in colorectal cancer. | 2020 |
1 |
| 21 |
32801295 | Sequential combinations of chemotherapeutic agents with BH3 mimetics to treat rhabdomyosarcoma and avoid resistance. | 2020 Aug 15 |
2 |
| 22 |
30008477 | The MCL1-specific inhibitor S63845 acts synergistically with venetoclax/ABT-199 to induce apoptosis in T-cell acute lymphoblastic leukemia cells. | 2019 Jan |
1 |
| 23 |
30214012 | Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia. | 2019 Apr |
1 |
| 24 |
31004002 | Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma. | 2019 Jul 15 |
1 |
| 25 |
31078737 | Combined Bcl-2/Src inhibition synergize to deplete stem-like breast cancer cells. | 2019 Aug 10 |
1 |
| 26 |
31856269 | Multiple myeloma with 1q21 amplification is highly sensitive to MCL-1 targeting. | 2019 Dec 23 |
1 |
| 27 |
28768804 | Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer. | 2017 Aug 2 |
2 |
| 28 |
27760111 | The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models. | 2016 Oct 27 |
1 |