fludarabine

MCL1 apoptosis regulator, BCL2 family member ; Homo sapiens







21 Article(s)
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1 35154579 ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells. 2022 1
2 34319043 MiRNA-Mediated Knock-Down of Bcl-2 and Mcl-1 Increases Fludarabine-Sensitivity in CLL-CII Cells. 2021 Jul 1 3
3 25804768 The MEK1/2 inhibitor, MEKi-1, induces cell death in chronic lymphocytic leukemia cells under conditions that mimic the tumor microenvironment and is synergistic with fludarabine. 2015 1
4 24495868 A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine. 2014 Jan 30 1
5 25111583 Synergistic cytotoxicity of sorafenib with busulfan and nucleoside analogs in human FMS-like tyrosine kinase 3 internal tandem duplications-positive acute myeloid leukemia cells. 2014 Nov 2
6 23681223 BECN1 and BIM interactions with MCL-1 determine fludarabine resistance in leukemic B cells. 2013 May 16 1
7 24141622 Synergistic apoptotic response between valproic acid and fludarabine in chronic lymphocytic leukaemia (CLL) cells involves the lysosomal protease cathepsin B. 2013 Oct 18 1
8 22072733 Leflunomide induces apoptosis in fludarabine-resistant and clinically refractory CLL cells. 2012 Jan 15 1
9 22128299 Tipping the Noxa/Mcl-1 balance overcomes ABT-737 resistance in chronic lymphocytic leukemia. 2012 Jan 15 1
10 22619113 The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-κB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells. 2012 May 1
11 21750559 Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation. 2011 Jul 12 1
12 20335218 Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia. 2010 Jun 3 1
13 18836097 AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance. 2009 Jan 1 1
14 19008456 Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab. 2009 Jan 15 1
15 19762485 Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance. 2009 Nov 12 1
16 18599795 Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers. 2008 Nov 1 2
17 16501812 Fludarabine induces apoptosis in chronic lymphocytic leukemia--the role of P53, Bcl-2, Bax, Mcl-1, and Bag-1 proteins. 2006 Mar 2
18 17018621 Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA. 2006 Oct 1 1
19 15059916 The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells. 2004 Apr 1 1
20 11472347 Flavopiridol circumvents Bcl-2 family mediated inhibition of apoptosis and drug resistance in B-cell chronic lymphocytic leukaemia. 2001 Jul 1
21 9558396 Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses. 1998 May 1 1