Title : AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance.

Pub. Date : 2009 Jan 1

PMID : 18836097






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Stromal cells protected CLL B cells from spontaneous and fludarabine-induced apoptosis (P = .003) by increasing the Mcl-1 protein levels. fludarabine MCL1 apoptosis regulator, BCL2 family member Homo sapiens