Title : Fractalkine deficiency attenuates LPS-induced acute kidney injury and podocyte apoptosis by targeting the PI3K/Akt signal pathway.

Pub. Date : 2022 Apr 8

PMID : 35394554






2 Functional Relationships(s)
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1 In cultured podocytes, we used plasmids to knockdown FKN and treated the podocytes with PI3K/Akt inhibitor (LY294002). 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one thymoma viral proto-oncogene 1 Mus musculus
2 FKN knockdown reduced podocyte apoptosis by regulating the Bcl-2 family; however, this protective effect was reversed by the co-administration of a PI3K/Akt inhibitor (LY294002). 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one thymoma viral proto-oncogene 1 Mus musculus