Cisplatin

thymoma viral proto-oncogene 1 ; Mus musculus







55 Article(s)
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1 35174550 Maltol mitigates cisplatin-evoked cardiotoxicity via inhibiting the PI3K/Akt signaling pathway in rodents in vivo and in vitro. 2022 Apr 1
2 35210433 c-Myb protects cochlear hair cells from cisplatin-induced damage via the PI3K/Akt signaling pathway. 2022 Feb 24 2
3 35236823 Extracellular ATP promotes breast cancer chemoresistance via HIF-1α signaling. 2022 Mar 2 1
4 35281608 Fuzheng Jiedu Decoction Induces Apoptosis and Enhances Cisplatin Efficacy in Ovarian Cancer Cells In Vitro and In Vivo through Inhibiting the PI3K/AKT/mTOR/NF-κB Signaling Pathway. 2022 3
5 35530288 β-elemene suppresses tumor metabolism and stem cell-like properties of non-small cell lung cancer cells by regulating PI3K/AKT/mTOR signaling. 2022 1
6 35548339 Phenethylisothiocyanate Potentiates Platinum Therapy by Reversing Cisplatin Resistance in Cervical Cancer. 2022 1
7 34077275 Resveratrol upregulates miR-455-5p to antagonize cisplatin ototoxicity via modulating the PTEN-PI3K-AKT axis. 2021 Jun 1
8 34268902 Exogenous insulin-like growth factor 1 attenuates cisplatin-induced muscle atrophy in mice. 2021 Dec 3
9 34381726 TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs. 2021 2
10 34461812 Protective Effect of 20(R)-Ginsenoside Rg3 Against Cisplatin-Induced Renal Toxicity via PI3K/AKT and NF-[Formula: see text]B Signaling Pathways Based on the Premise of Ensuring Anticancer Effect. 2021 1
11 34580062 A PLCB1-PI3K-AKT Signaling Axis Activates EMT to Promote Cholangiocarcinoma Progression. 2021 Dec 1 1
12 34671212 Long non-coding RNA MEG3 promotes cisplatin-induced nephrotoxicity through regulating AKT/TSC/mTOR-mediated autophagy. 2021 2
13 31961716 Inhibition of PDE4/PDE4B improves renal function and ameliorates inflammation in cisplatin-induced acute kidney injury. 2020 Mar 1 1
14 32039764 Ivermectin Augments the In Vitro and In Vivo Efficacy of Cisplatin in Epithelial Ovarian Cancer by Suppressing Akt/mTOR Signaling. 2020 Feb 1
15 32150448 Canagliflozin reduces cisplatin uptake and activates Akt to protect against cisplatin-induced nephrotoxicity. 2020 Apr 1 1
16 32252554 Cucurbitacin B and cisplatin induce the cell death pathways in MB49 mouse bladder cancer model. 2020 May 1
17 32280245 The Metastasis Potential Promoting Capacity of Cancer-Associated Fibroblasts Was Attenuated by Cisplatin via Modulating KRT8. 2020 3
18 33227065 AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity. 2020 Nov 10 4
19 33272245 MNAT1 promotes proliferation and the chemo-resistance of osteosarcoma cell to cisplatin through regulating PI3K/Akt/mTOR pathway. 2020 Dec 3 1
20 33390985 Linalool Prevents Cisplatin Induced Muscle Atrophy by Regulating IGF-1/Akt/FoxO Pathway. 2020 1
21 30387162 TLR2 protects cisplatin-induced acute kidney injury associated with autophagy via PI3K/Akt signaling pathway. 2019 Mar 4
22 30975980 Akt inhibitor SC66 promotes cell sensitivity to cisplatin in chemoresistant ovarian cancer cells through inhibition of COL11A1 expression. 2019 Apr 11 1
23 31320816 Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice. 2019 2
24 31781349 Remote Ischemic Preconditioning Protects Cisplatin-Induced Acute Kidney Injury through the PTEN/AKT Signaling Pathway. 2019 1
25 29110119 Metformin synergistically enhances antitumor activity of cisplatin in gallbladder cancer via the PI3K/AKT/ERK pathway. 2018 Feb 1
26 29284644 COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin. 2018 Feb 1
27 29556279 HSPA12B overexpression induces cisplatin resistance in non-small-cell lung cancer by regulating the PI3K/Akt/NF-κB signaling pathway. 2018 Mar 1
28 30121639 High Platelet Levels Attenuate the Efficacy of Platinum-Based Treatment in Non-Small Cell Lung Cancer. 2018 2
29 30235825 Platycodon grandiflorum Saponins Ameliorate Cisplatin-Induced Acute Nephrotoxicity through the NF-κB-Mediated Inflammation and PI3K/Akt/Apoptosis Signaling Pathways. 2018 Sep 19 1
30 30374107 The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways. 2018 Oct 29 1
31 27799485 Protein Kinase Cδ Suppresses Autophagy to Induce Kidney Cell Apoptosis in Cisplatin Nephrotoxicity. 2017 Apr 9
32 28255274 Hyperhomocysteinemia Exacerbates Cisplatin-induced Acute Kidney Injury. 2017 1
33 28762162 Effect of acute treadmill exercise on cisplatin-induced muscle atrophy in the mouse. 2017 Nov 1
34 26882203 Melatonin prevents cisplatin-induced primordial follicle loss via suppression of PTEN/AKT/FOXO3a pathway activation in the mouse ovary. 2016 Apr 3
35 27825756 Carvacrol attenuates acute kidney injury induced by cisplatin through suppression of ERK and PI3K/Akt activation. 2016 Dec 1
36 27876874 TWIST1 drives cisplatin resistance and cell survival in an ovarian cancer model, via upregulation of GAS6, L1CAM, and Akt signalling. 2016 Nov 23 3
37 25978595 Liquiritigenin Potentiates the Inhibitory Effects of Cisplatin on Invasion and Metastasis Via Downregulation MMP-2/9 and PI3 K/AKT Signaling Pathway in B16F10 Melanoma Cells and Mice Model. 2015 2
38 26136189 Ghrelin prevents tumour- and cisplatin-induced muscle wasting: characterization of multiple mechanisms involved. 2015 Jun 1
39 26656301 Cisplatin Induces Overactivation of the Dormant Primordial Follicle through PTEN/AKT/FOXO3a Pathway which Leads to Loss of Ovarian Reserve in Mice. 2015 4
40 24823295 Mechanisms of cisplatin-induced muscle atrophy. 2014 Jul 15 2
41 25071019 Sensitization of ovarian cancer cells to cisplatin by gold nanoparticles. 2014 Aug 15 1
42 25282897 [Effect of Buzhong Yiqi decoction on PI3K and AKT in spleen, stomach and lung of nude mice with lung adenocarcinoma transplantation tumor]. 2014 May 5
43 23095324 Molecular imaging reveals a role for AKT in resistance to cisplatin for ovarian endometrioid adenocarcinoma. 2013 Jan 1 1
44 24130050 Tunicamycin potentiates cisplatin anticancer efficacy through the DPAGT1/Akt/ABCG2 pathway in mouse Xenograft models of human hepatocellular carcinoma. 2013 Dec 3
45 22760211 Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin's antitumor activity in vivo. 2012 Nov 6
46 21074548 Cisplatin triggers atrophy of skeletal C2C12 myotubes via impairment of Akt signalling pathway and subsequent increment activity of proteasome and autophagy systems. 2011 Feb 1 4
47 22096562 The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma. 2011 2
48 20506484 PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice. 2010 Sep 1 1
49 18046317 The phosphoinositide-3 kinase gamma-Akt pathway mediates renal tubular injury in cisplatin nephrotoxicity. 2008 Feb 2
50 18364504 Autocrine and paracrine chemokine receptor 7 activation in head and neck cancer: implications for therapy. 2008 Apr 2 1