Title : Phenethylisothiocyanate Potentiates Platinum Therapy by Reversing Cisplatin Resistance in Cervical Cancer.

Pub. Date : 2022

PMID : 35548339






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Acquired cisplatin resistance in cervical cancer therapy is principally caused by reduction in intracellular drug accumulation, which is exerted by hyperactivation of the oncogenic PI3K/Akt signaling axis and overexpression of cisplatin-exporter MRP2 along with prosurvival effectors NF-kappaB and IAPs in cervical cancer cells. Cisplatin thymoma viral proto-oncogene 1 Mus musculus