Cisplatin

cytochrome c, somatic ; Homo sapiens







82 Article(s)
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51 17311906 Mcl-1 is downregulated in cisplatin-induced apoptosis, and proteasome inhibitors restore Mcl-1 and promote survival in renal tubular epithelial cells. 2007 Jun 2
52 17363497 Bortezomib, but not cisplatin, induces mitochondria-dependent apoptosis accompanied by up-regulation of noxa in the non-small cell lung cancer cell line NCI-H460. 2007 Mar 1
53 17603269 [Molecular basis for the inhibition of anticancer agents-induced apoptosis by thymidine phosphorylase]. 2007 Jul 1
54 17619073 Solamargine induces apoptosis and sensitizes breast cancer cells to cisplatin. 2007 Nov 2
55 16009487 Upregulation of Bcl-2 is associated with cisplatin-resistance via inhibition of Bax translocation in human bladder cancer cells. 2006 Jun 8 1
56 16442262 Role of death receptor and mitochondrial pathways in conventional chemotherapy drug induction of apoptosis. 2006 Sep 1
57 16540663 Akt-mediated cisplatin resistance in ovarian cancer: modulation of p53 action on caspase-dependent mitochondrial death pathway. 2006 Mar 15 1
58 16855374 Dexamethasone protects against Cisplatin-induced activation of the mitochondrial apoptotic pathway in human osteosarcoma cells. 2006 Aug 1
59 15870947 Defects in apoptotic signal transduction in cisplatin-resistant non-small cell lung cancer cells. 2005 Jun 1
60 15965098 Enhancement of cisplatin-induced apoptosis and caspase 3 activation by depletion of mitochondrial DNA in a human osteosarcoma cell line. 2005 May 2
61 16228292 BCL-2 antisense and cisplatin combination treatment of MCF-7 breast cancer cells with or without functional p53. 2005 Dec 1
62 15153331 Glutathione depletion induced by c-Myc downregulation triggers apoptosis on treatment with alkylating agents. 2004 May-Jun 1
63 15604295 Caspase inhibitors, but not c-Jun NH2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss. 2004 Dec 15 1
64 12543167 Inhibition of caspase-9 activity and Apaf-1 expression in cisplatin-resistant head and neck squamous cell carcinoma cells. 2003 Feb 1
65 12618201 Cisplatin induces apoptosis in oral squamous carcinoma cells by the mitochondria-mediated but not the NF-kappaB-suppressed pathway. 2003 Apr 1
66 12867996 The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells. 2003 Aug 1
67 12893210 Enhancement of sensitivity to cisplatin by orobol is associated with increased mitochondrial cytochrome c release in human ovarian carcinoma cells. 2003 Aug 1
68 11895373 Cisplatin-induced apoptosis of DRG neurons involves bax redistribution and cytochrome c release but not fas receptor signaling. 2002 Mar 2
69 11895917 Rituximab modifies the cisplatin-mitochondrial signaling pathway, resulting in apoptosis in cisplatin-resistant non-Hodgkin's lymphoma. 2002 Mar 1
70 11905052 [Inhibition of caspase-9 activity in cisplatin-resistant head and neck squamous cell carcinoma]. 2002 Feb 4
71 12018840 Signaling and function of caspase and c-jun N-terminal kinase in cisplatin-induced apoptosis. 2002 Apr 30 2
72 12060385 Drug resistance towards etoposide and cisplatin in human melanoma cells is associated with drug-dependent apoptosis deficiency. 2002 Jun 2
73 12667321 [Relationship between cytochrome c-mediated caspase-3 activity and chemoresistance in cisplatin-resistant human ovarian cancer cell lines]. 2002 Nov 6
74 11340162 Cisplatin induces the proapoptotic conformation of Bak in a deltaMEKK1-dependent manner. 2001 Jun 1
75 11368186 Targeting superoxide dismutase to renal proximal tubule cells inhibits mitochondrial injury and renal dysfunction inuduced by cisplatin. 2001 Mar 1 1
76 11566177 Apaf-1 overexpression partially overcomes apoptotic resistance in a cisplatin-selected HeLa cell line. 2001 Sep 14 1
77 11774739 Mitochondria in platinum resistant cells. 2001 Sep 2
78 10918609 Influence of Bax or Bcl-2 overexpression on the ceramide-dependent apoptotic pathway in glioma cells. 2000 Jul 20 1
79 10969782 Caspase-3 is essential for procaspase-9 processing and cisplatin-induced apoptosis of MCF-7 breast cancer cells. 2000 Aug 15 1
80 10993883 Requirement for ERK activation in cisplatin-induced apoptosis. 2000 Dec 15 1
81 10397248 Cisplatin-induced apoptosis proceeds by caspase-3-dependent and -independent pathways in cisplatin-resistant and -sensitive human ovarian cancer cell lines. 1999 Jul 1 2
82 9014341 Studies on the interaction between cytochrome c and cis-PtCl2(NH3)2. 1997 Feb 1 5