Title : Overexpression of optic atrophy 1 protein increases cisplatin resistance via inactivation of caspase-dependent apoptosis in lung adenocarcinoma cells.

Pub. Date : 2012 Jan

PMID : 21798574






1 Functional Relationships(s)
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1 In the in vitro experiments with cell lines, silencing of optic atrophy 1 expression reduced cisplatin resistance, which was further shown via increased release of cytochrome c and activation of caspase-dependent apoptotic pathway. Cisplatin cytochrome c, somatic Homo sapiens