| 1 |
30991803 | Hybrid QM/MM vs Pure MM Molecular Dynamics for Evaluating Water Distribution within p21N-ras and the Resulting GTP Electronic Density. | 2019 May 9 |
1 |
| 2 |
29719614 | The microdomain-organizing protein MPP1 is required for insulin-stimulated activation of H-Ras. | 2018 Apr 6 |
1 |
| 3 |
27820802 | Inhibition of RAS function through targeting an allosteric regulatory site. | 2017 Jan |
1 |
| 4 |
26373425 | 1H, 15N and 13C backbone assignments of GDP-bound human H-Ras mutant G12V. | 2016 Apr |
1 |
| 5 |
27412770 | Dynamic studies of H-Ras•GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution. | 2016 Jul 14 |
1 |
| 6 |
25776558 | H-ras distribution and signaling in plasma membrane microdomains are regulated by acylation and deacylation events. | 2015 Jun 1 |
1 |
| 7 |
25846136 | Differential dynamics of RAS isoforms in GDP- and GTP-bound states. | 2015 Jun |
1 |
| 8 |
25272152 | Mechanism of the exchange reaction in HRAS from multiscale modeling. | 2014 |
2 |
| 9 |
23335589 | Functional analysis of a duplication (p.E63_D69dup) in the switch II region of HRAS: new aspects of the molecular pathogenesis underlying Costello syndrome. | 2013 Apr 15 |
1 |
| 10 |
21768877 | Relationship between expression of ras p21 oncoprotein and mutation status of the K-ras gene in sporadic colorectal cancer patients in Tunisia. | 2012 Mar |
1 |
| 11 |
19995790 | Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation. | 2010 Mar 1 |
1 |
| 12 |
20479006 | Structural basis for conformational dynamics of GTP-bound Ras protein. | 2010 Jul 16 |
2 |
| 13 |
20858867 | Regulation of Ras localization by acylation enables a mode of intracellular signal propagation. | 2010 Sep 21 |
1 |
| 14 |
19035362 | Oncogenic HRAS mutations cause prolonged PI3K signaling in response to epidermal growth factor in fibroblasts of patients with Costello syndrome. | 2009 Mar |
1 |
| 15 |
18790720 | Binding of calcium ions to Ras promotes Ras guanine nucleotide exchange under emulated physiological conditions. | 2008 Nov |
2 |
| 16 |
16866878 | Crystal structure of human Rad GTPase of the RGK-family. | 2006 Aug |
2 |
| 17 |
15812354 | Transient activation of Ras-dependent signalling at the early stages of Herbimycin A induced erythroid differentiation of human K562 cells. | 2005 Mar |
1 |
| 18 |
15287738 | pH-dependent perturbation of Ras-guanine nucleotide interactions and Ras guanine nucleotide exchange. | 2004 Aug 10 |
1 |
| 19 |
12006650 | Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells. | 2002 May |
1 |
| 20 |
11283610 | GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. | 2001 Apr |
1 |
| 21 |
11676197 | The upregulation by peplomycin of signal transduction in human cells. | 2001 Sep |
1 |
| 22 |
10208427 | Isoform-specific insertion near the Grb2-binding domain modulates the intrinsic guanine nucleotide exchange activity of hSos1. | 1999 Mar 4 |
1 |
| 23 |
9760267 | Transient kinetic studies on the interaction of Ras and the Ras-binding domain of c-Raf-1 reveal rapid equilibration of the complex. | 1998 Oct 6 |
2 |
| 24 |
9778365 | The role of ligand binding in the kinetic folding mechanism of human p21(H-ras) protein. | 1998 Oct 20 |
4 |
| 25 |
9219684 | The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. | 1997 Jul 18 |
1 |
| 26 |
9312017 | Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS. | 1997 Sep 15 |
1 |
| 27 |
9404480 | RAS and the myelodysplastic syndromes. | 1997 Sep |
1 |
| 28 |
8740369 | Electrostatic control of GTP and GDP binding in the oncoprotein p21ras. | 1996 Apr 15 |
3 |
| 29 |
8744572 | Structural basis of p21H-ras molecular switch inhibition by a neutralizing antibody. | 1996 Feb |
1 |
| 30 |
8974153 | Ha-ras in normal and tumoral tissues: structure, function and regulation. | 1996 Sep |
1 |
| 31 |
7706235 | Nitric oxide-stimulated guanine nucleotide exchange on p21ras. | 1995 Mar 31 |
1 |
| 32 |
7819254 | Substrate and product structural requirements for binding of nucleotides to H-ras p21: the mechanism of discrimination between guanosine and adenosine nucleotides. | 1995 Jan 17 |
1 |
| 33 |
7819259 | Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1. | 1995 Jan 17 |
2 |
| 34 |
7852367 | Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase. | 1995 Feb 17 |
1 |
| 35 |
7787254 | Biological activity of human N-ras and K-ras genes containing the Asn17 dominant negative mutation. | 1994 |
1 |
| 36 |
8136358 | Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study. | 1994 Mar 22 |
1 |
| 37 |
8257693 | Solution dynamics of p21ras proteins bound with fluorescent nucleotides: a time-resolved fluorescence study. | 1993 Dec 14 |
1 |
| 38 |
8338834 | An NMR comparison of the changes produced by different guanosine 5'-triphosphate analogs in wild-type and oncogenic mutant p21ras. | 1993 Jul 27 |
5 |
| 39 |
8353139 | Role of GTPases and GTPase regulatory proteins in oncogenesis. | 1993 |
1 |
| 40 |
8386636 | Nucleotide binding and GTP hydrolysis by the 21-kDa product of the c-H-ras gene as monitored by proton-NMR spectroscopy. | 1993 Apr 15 |
1 |
| 41 |
8388384 | Insulin stimulates association of insulin receptor substrate-1 with the protein abundant Src homology/growth factor receptor-bound protein 2. | 1993 May 25 |
1 |
| 42 |
8444185 | Epidermal-growth-factor receptors generate Ras.GTP more efficiently than insulin receptors. | 1993 Mar 1 |
1 |
| 43 |
8486615 | Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target. | 1993 May 5 |
1 |
| 44 |
1420142 | NMR studies of the conformational change in human N-p21ras produced by replacement of bound GDP with the GTP analog GTP gamma S. | 1992 Oct 27 |
3 |
| 45 |
1421163 | Three-dimensional structure of p21H-ras and its implications. | 1992 Aug |
1 |
| 46 |
1608472 | Involvement of p21ras in activation of extracellular signal-regulated kinase 2. | 1992 Jun 18 |
1 |
| 47 |
1633420 | Regulation of p21ras by GTPase activating proteins and guanine nucleotide exchange proteins. | 1992 Feb |
2 |
| 48 |
1741165 | Isolation of azatyrosine-induced revertants from ras-transformed human mammary epithelial cells. | 1992 Jan |
1 |
| 49 |
1703633 | Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein. | 1991 Feb |
1 |
| 50 |
1850098 | The epidermal growth factor receptor phosphorylates GTPase-activating protein (GAP) at Tyr-460, adjacent to the GAP SH2 domains. | 1991 May |
1 |