Title : Regulation of Ras localization by acylation enables a mode of intracellular signal propagation.

Pub. Date : 2010 Sep 21

PMID : 20858867






1 Functional Relationships(s)
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1 Two overlapping regulatory networks control compartmentalized H-Ras activity: the guanosine diphosphate-guanosine triphosphate cycle and the acylation cycle, which constitutively traffics Ras isoforms that can be palmitoylated between intracellular membrane compartments. Guanosine Diphosphate HRas proto-oncogene, GTPase Homo sapiens