Title : H-ras distribution and signaling in plasma membrane microdomains are regulated by acylation and deacylation events.

Pub. Date : 2015 Jun 1

PMID : 25776558






1 Functional Relationships(s)
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1 At the plasma membrane, H-Ras has been proposed to occupy distinct sublocations, depending on its activation status: lipid rafts/detergent-resistant membrane fractions when bound to GDP, diffusing to disordered membrane/soluble fractions in response to GTP loading. Guanosine Diphosphate HRas proto-oncogene, GTPase Homo sapiens