| 1 |
35491445 | VWF-Gly2752Ser, a novel non-cysteine substitution variant in the CK domain, exhibits severe secretory impairment by hampering C-terminal dimer formation. | 2022 May 1 |
1 |
| 2 |
33588457 | Functional Roles of the von Willebrand Factor Propeptide. | 2021 Feb |
1 |
| 3 |
34838051 | The disulfide bond Cys2724-Cys2774 in the C-terminal cystine knot domain of von Willebrand factor is critical for its dimerization and secretion. | 2021 Nov 27 |
2 |
| 4 |
31479573 | Glycosylation sterically inhibits platelet adhesion to von Willebrand factor without altering intrinsic conformational dynamics. | 2020 Jan |
1 |
| 5 |
30642920 | The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis. | 2019 Apr 4 |
3 |
| 6 |
30936056 | von Willebrand factor self-association is regulated by the shear-dependent unfolding of the A2 domain. | 2019 Apr 9 |
1 |
| 7 |
29507883 | Autoregulation of von Willebrand factor function by a disulfide bond switch. | 2018 Feb |
4 |
| 8 |
30351116 | Correlating Conformational Dynamics with the Von Willebrand Factor Reductase Activity of Factor H Using Single Molecule Force Measurements. | 2018 Nov 29 |
2 |
| 9 |
31080944 | Complement Component C3 Binds to the A3 Domain of von Willebrand Factor. | 2018 |
1 |
| 10 |
28139814 | Von Willebrand factor processing. | 2017 Jan 31 |
1 |
| 11 |
28533135 | Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet Clumping. | 2017 Jul 7 |
3 |
| 12 |
29059501 | Head-to-Tail Cyclic Peptide Inhibitors of the Interaction between Human von Willebrand Factor and Collagen. | 2017 Dec 7 |
1 |
| 13 |
26581637 | Free thiol groups in von Willebrand factor (VWF) are required for its full function under physiological flow conditions. | 2016 Jan |
1 |
| 14 |
26670633 | von Willebrand factor is dimerized by protein disulfide isomerase. | 2016 Mar 3 |
3 |
| 15 |
26099845 | Industrial production of clotting factors: Challenges of expression, and choice of host cells. | 2015 Jul |
1 |
| 16 |
24283831 | The von Willebrand factor predicted unpaired cysteines are essential for secretion. | 2014 Feb |
1 |
| 17 |
22207689 | Biogenesis of Weibel-Palade bodies in von Willebrand's disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation. | 2012 Jun |
1 |
| 18 |
22490677 | Sequence and structure relationships within von Willebrand factor. | 2012 Jul 12 |
1 |
| 19 |
23067373 | The unfolded von Willebrand factor response in bloodstream: the self-association perspective. | 2012 Oct 15 |
2 |
| 20 |
21266777 | N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice. | 2011 Feb |
2 |
| 21 |
21507943 | Platelet glycoprotein Ib beta/IX mediates glycoprotein Ib alpha localization to membrane lipid domain critical for von Willebrand factor interaction at high shear. | 2011 Jun 17 |
1 |
| 22 |
21911836 | Lateral self-association of VWF involves the Cys2431-Cys2453 disulfide/dithiol in the C2 domain. | 2011 Nov 10 |
7 |
| 23 |
20354169 | The importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain function. | 2010 Jun 10 |
2 |
| 24 |
20705333 | Thrombospondin-1 and ADAMTS13 competitively bind to VWF A2 and A3 domains in vitro. | 2010 Oct |
4 |
| 25 |
20946172 | Disulfide bond reduction of von Willebrand factor by ADAMTS-13. | 2010 Dec |
10 |
| 26 |
20979592 | Redox control of β2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1. | 2010 Aug |
1 |
| 27 |
19630761 | von Willebrand factor assembly and secretion. | 2009 Jul |
2 |
| 28 |
19817991 | Shear-induced unfolding activates von Willebrand factor A2 domain for proteolysis. | 2009 Dec |
2 |
| 29 |
18182488 | Assembly of Weibel-Palade body-like tubules from N-terminal domains of von Willebrand factor. | 2008 Jan 15 |
1 |
| 30 |
17895385 | Two Cys residues essential for von Willebrand factor multimer assembly in the Golgi. | 2007 Oct 2 |
5 |
| 31 |
17925407 | Shear-induced disulfide bond formation regulates adhesion activity of von Willebrand factor. | 2007 Dec 7 |
4 |
| 32 |
16409464 | Mutations C1157F and C1234W of von Willebrand factor cause intracellular retention with defective multimerization and secretion. | 2006 Jan |
2 |
| 33 |
16706977 | Intrinsic stability and functional properties of disulfide bond-stabilized coagulation factor VIIIa variants. | 2006 Jun |
3 |
| 34 |
17139364 | Differential effects of the loss of intrachain- versus interchain-disulfide bonds in the cystine-knot domain of von Willebrand factor on the clinical phenotype of von Willebrand disease. | 2006 Dec |
9 |
| 35 |
16102036 | von Willebrand factor: two sides of a coin. | 2005 Aug |
1 |
| 36 |
14755371 | C1272S: a new candidate mutation in type 2A von Willebrand disease that disrupts the disulfide loop responsible for the interaction of VWF with platelet GP Ib-IX. | 2004 Feb |
2 |
| 37 |
15507277 | Platelet physiology and thrombosis. | 2004 |
1 |
| 38 |
11943773 | Identification of the regulatory elements of the human von Willebrand factor for binding to platelet GPIb. Importance of structural integrity of the regions flanked by the CYS1272-CYS1458 disulfide bond. | 2002 Jun 14 |
1 |
| 39 |
12351392 | The von Willebrand factor-reducing activity of thrombospondin-1 is located in the calcium-binding/C-terminal sequence and requires a free thiol at position 974. | 2002 Oct 15 |
2 |
| 40 |
11264172 | Expression and characterization of von Willebrand factor dimerization defects in different types of von Willebrand disease. | 2001 Apr 1 |
2 |
| 41 |
11816713 | A novel monoclonal antibody against the extracellular domain of GPIbbeta modulates vWF mediated platelet adhesion. | 2001 Nov |
2 |
| 42 |
10831592 | Localization of disulfide bonds in the cystine knot domain of human von Willebrand factor. | 2000 Aug 18 |
1 |
| 43 |
11019979 | Reduction of von Willebrand factor by endothelial cells. | 2000 Sep |
2 |
| 44 |
9473222 | Type 2M von Willebrand disease: F606I and I662F mutations in the glycoprotein Ib binding domain selectively impair ristocetin- but not botrocetin-mediated binding of von Willebrand factor to platelets. | 1998 Mar 1 |
1 |
| 45 |
9603957 | Porcine submaxillary mucin forms disulfide-linked multimers through its amino-terminal D-domains. | 1998 Jun 5 |
1 |
| 46 |
9657753 | Binding of factor VIII to von willebrand factor is enabled by cleavage of the von Willebrand factor propeptide and enhanced by formation of disulfide-linked multimers. | 1998 Jul 15 |
4 |
| 47 |
9759493 | Biochemistry and genetics of von Willebrand factor. | 1998 |
1 |
| 48 |
9129011 | Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura. | 1997 May 1 |
2 |
| 49 |
8622978 | Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease. | 1996 Apr 16 |
3 |
| 50 |
8639781 | Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis. | 1996 May 15 |
1 |