1,N(6)-ethenoadenine

N-methylpurine DNA glycosylase ; Homo sapiens







28 Article(s)
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1 31882538 Recognition of 1,N 2-ethenoguanine by alkyladenine DNA glycosylase is restricted by a conserved active-site residue. 2020 Feb 7 2
2 31310499 Global Repair Profile of Human Alkyladenine DNA Glycosylase on Nucleosomes Reveals DNA Packaging Effects. 2019 Aug 16 2
3 27025273 The formation of catalytically competent enzyme-substrate complex is not a bottleneck in lesion excision by human alkyladenine DNA glycosylase. 2017 Apr 1
4 25538240 Germ line variants of human N-methylpurine DNA glycosylase show impaired DNA repair activity and facilitate 1,N6-ethenoadenine-induced mutations. 2015 Feb 20 3
5 25355292 Enzymatic MPG DNA repair assays for two different oxidative DNA lesions reveal associations with increased lung cancer risk. 2014 Dec 2
6 22079122 Direct repair of 3,N(4)-ethenocytosine by the human ALKBH2 dioxygenase is blocked by the AAG/MPG glycosylase. 2012 Jan 2 6
7 21349833 Structural basis for the inhibition of human alkyladenine DNA glycosylase (AAG) by 3,N4-ethenocytosine-containing DNA. 2011 Apr 15 2
8 22041025 XRCC1 and base excision repair balance in response to nitric oxide. 2011 Dec 10 1
9 20873830 N-glycosyl bond formation catalyzed by human alkyladenine DNA glycosylase. 2010 Oct 26 2
10 19219989 Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG). 2009 Mar 10 2
11 19616486 Excised damaged base determines the turnover of human N-methylpurine-DNA glycosylase. 2009 Oct 2 1
12 17768096 Discrimination of lesion removal of N-methylpurine-DNA glycosylase revealed by a potent neutralizing monoclonal antibody. 2008 Jan 1 1
13 18593189 The acidity and proton affinity of the damaged base 1,N6-ethenoadenine in the gas phase versus in solution: intrinsic reactivity and biological implications. 2008 Aug 1 1
14 17018265 Slow base excision by human alkyladenine DNA glycosylase limits the rate of formation of AP sites and AP endonuclease 1 does not stimulate base excision. 2007 Jan 4 2
15 16938414 Metal inhibition of human N-methylpurine-DNA glycosylase activity in base excision repair. 2006 Oct 25 2
16 15990363 The efficiency of hypoxanthine excision by alkyladenine DNA glycosylase is altered by changes in nearest neighbor bases. 2005 Sep 28 2
17 14729667 The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N6-ethenoadenine as preferred substrates. 2004 Apr 2 1
18 15247209 Oxanine DNA glycosylase activity from Mammalian alkyladenine glycosylase. 2004 Sep 10 1
19 12566303 Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing. 2003 Feb 1 2
20 14567703 Human alkyladenine DNA glycosylase uses acid-base catalysis for selective excision of damaged purines. 2003 Oct 28 1
21 12323378 Active-site clashes prevent the human 3-methyladenine DNA glycosylase from improperly removing bases. 2002 Sep 2
22 10891085 Cisplatin adducts inhibit 1,N(6)-ethenoadenine repair by interacting with the human 3-methyladenine DNA glycosylase. 2000 Jul 11 2
23 10980409 Promoter structure and cell cycle dependent expression of the human methylpurine-DNA glycosylase gene. 2000 Sep 15 2
24 11106395 Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. 2000 Dec 5 1
25 10329732 The type of DNA glycosylase determines the base excision repair pathway in mammalian cells. 1999 May 21 1
26 9837917 Correlation between sequence-dependent glycosylase repair and the thermal stability of oligonucleotide duplexes containing 1, N6-ethenoadenine. 1998 Dec 11 2
27 8110764 1,N6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase). 1994 Feb 22 1
28 1409645 Both purified human 1,N6-ethenoadenine-binding protein and purified human 3-methyladenine-DNA glycosylase act on 1,N6-ethenoadenine and 3-methyladenine. 1992 Oct 15 4