Title : Discrimination of lesion removal of N-methylpurine-DNA glycosylase revealed by a potent neutralizing monoclonal antibody.

Pub. Date : 2008 Jan 1

PMID : 17768096






1 Functional Relationships(s)
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1 We found that moAb 520-3A significantly inhibited MPG"s enzymatic activity towards different substrates, such as hypoxanthine, 1,N(6)ethenoadenine and methylated bases, which represent different classes of DNA damage, however, with different efficiencies. 1,N(6)-ethenoadenine N-methylpurine DNA glycosylase Homo sapiens