Title : Direct repair of 3,N(4)-ethenocytosine by the human ALKBH2 dioxygenase is blocked by the AAG/MPG glycosylase.

Pub. Date : 2012 Jan 2

PMID : 22079122






6 Functional Relationships(s)
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Protein Name
Organism
1 While the alkyladenine DNA glycosylase, AAG (or MPG), binds the etheno lesions 1,N(6)-ethenoadenine (eA) and 3,N(4)-ethenocytosine (eC) with high affinity, only eA can be excised to initiate base excision repair. 1,N(6)-ethenoadenine N-methylpurine DNA glycosylase Homo sapiens
2 While the alkyladenine DNA glycosylase, AAG (or MPG), binds the etheno lesions 1,N(6)-ethenoadenine (eA) and 3,N(4)-ethenocytosine (eC) with high affinity, only eA can be excised to initiate base excision repair. 1,N(6)-ethenoadenine N-methylpurine DNA glycosylase Homo sapiens
3 While the alkyladenine DNA glycosylase, AAG (or MPG), binds the etheno lesions 1,N(6)-ethenoadenine (eA) and 3,N(4)-ethenocytosine (eC) with high affinity, only eA can be excised to initiate base excision repair. 1,N(6)-ethenoadenine N-methylpurine DNA glycosylase Homo sapiens
4 While the alkyladenine DNA glycosylase, AAG (or MPG), binds the etheno lesions 1,N(6)-ethenoadenine (eA) and 3,N(4)-ethenocytosine (eC) with high affinity, only eA can be excised to initiate base excision repair. 1,N(6)-ethenoadenine N-methylpurine DNA glycosylase Homo sapiens
5 While the alkyladenine DNA glycosylase, AAG (or MPG), binds the etheno lesions 1,N(6)-ethenoadenine (eA) and 3,N(4)-ethenocytosine (eC) with high affinity, only eA can be excised to initiate base excision repair. 1,N(6)-ethenoadenine N-methylpurine DNA glycosylase Homo sapiens
6 While the alkyladenine DNA glycosylase, AAG (or MPG), binds the etheno lesions 1,N(6)-ethenoadenine (eA) and 3,N(4)-ethenocytosine (eC) with high affinity, only eA can be excised to initiate base excision repair. 1,N(6)-ethenoadenine N-methylpurine DNA glycosylase Homo sapiens