| 1 |
33617900 | SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function. | 2021 Apr 16 |
1 |
| 2 |
34062268 | The C-type lectin CD93 controls endothelial cell migration via activation of the Rho family of small GTPases. | 2021 May |
1 |
| 3 |
34157521 | Epidermal growth factor receptor and integrins meet redox signaling through P66shc and Rac1. | 2021 Oct |
2 |
| 4 |
29498112 | Phosphorylation control of the ubiquitin ligase Cbl is conserved in choanoflagellates. | 2018 May |
1 |
| 5 |
26848865 | CD93 and dystroglycan cooperation in human endothelial cell adhesion and migration adhesion and migration. | 2016 Mar 1 |
1 |
| 6 |
27048651 | The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling. | 2016 May 27 |
1 |
| 7 |
27261451 | Personalized medicine in cystic fibrosis: genistein supplementation as a treatment option for patients with a rare S1045Y-CFTR mutation. | 2016 Aug 1 |
2 |
| 8 |
27725776 | Leukocyte immunoglobulin-like receptor B4 regulates key signalling molecules involved in FcγRI-mediated clathrin-dependent endocytosis and phagocytosis. | 2016 Oct 11 |
1 |
| 9 |
26104663 | A point mutation of zebrafish c-cbl gene in the ring finger domain produces a phenotype mimicking human myeloproliferative disease. | 2015 Dec |
1 |
| 10 |
26363459 | Functional requirement of tyrosine residue 429 within CD5 cytoplasmic domain for regulation of T cell activation and survival. | 2015 Oct 23 |
1 |
| 11 |
26609808 | EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling. | 2015 Nov 26 |
1 |
| 12 |
24876153 | Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility. | 2014 Aug |
1 |
| 13 |
24886428 | A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis. | 2014 May 7 |
5 |
| 14 |
24985478 | Antagonizing c-Cbl enhances EGFR-dependent corneal epithelial homeostasis. | 2014 Jul 1 |
1 |
| 15 |
25084697 | Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase. | 2014 Dec |
2 |
| 16 |
25387128 | N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain. | 2014 |
1 |
| 17 |
23027125 | HER2 stabilizes EGFR and itself by altering autophosphorylation patterns in a manner that overcomes regulatory mechanisms and promotes proliferative and transformation signaling. | 2013 Aug 29 |
1 |
| 18 |
23352614 | PTK6 promotes degradation of c-Cbl through PTK6-mediated phosphorylation. | 2013 Feb 22 |
3 |
| 19 |
23774213 | CTEN prolongs signaling by EGFR through reducing its ligand-induced degradation. | 2013 Aug 15 |
1 |
| 20 |
23991943 | Tyrosine 1045 codon mutations in exon 27 of EGFR are infrequent in oral squamous cell carcinomas. | 2013 |
1 |
| 21 |
22266821 | Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl. | 2012 Jan 22 |
1 |
| 22 |
22542851 | Raft coalescence and FcγRIIA activation upon sphingomyelin clustering induced by lysenin. | 2012 Aug |
1 |
| 23 |
22665495 | Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics. | 2012 Aug |
1 |
| 24 |
20940296 | Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration. | 2011 Jan 7 |
4 |
| 25 |
21163258 | An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding. | 2011 Jan 21 |
4 |
| 26 |
21625213 | HPV16 E5 affects the KGFR/FGFR2b-mediated epithelial growth through alteration of the receptor expression, signaling and endocytic traffic. | 2011 Dec 15 |
1 |
| 27 |
21905200 | CD43 regulates the threshold for T cell activation by targeting Cbl functions. | 2011 Oct |
1 |
| 28 |
20071559 | Progesterone inhibits glucose uptake by affecting diverse steps of insulin signaling in 3T3-L1 adipocytes. | 2010 Apr |
2 |
| 29 |
20082303 | Quercetin suppresses HeLa cell viability via AMPK-induced HSP70 and EGFR down-regulation. | 2010 May |
1 |
| 30 |
20236940 | Activation of vascular endothelial growth factor receptor 2 in a cellular model of loricrin keratoderma. | 2010 May 21 |
1 |
| 31 |
21203488 | Interaction of c-Cbl with myosin IIA regulates Bleb associated macropinocytosis of Kaposi's sarcoma-associated herpesvirus. | 2010 Dec 23 |
2 |
| 32 |
18951974 | Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop. | 2009 Feb |
1 |
| 33 |
19419964 | Syk tyrosine 317 negatively regulates osteoclast function via the ubiquitin-protein isopeptide ligase activity of Cbl. | 2009 Jul 10 |
1 |
| 34 |
19450681 | Phosphorylation of the MET receptor on juxtamembrane tyrosine residue 1001 inhibits its caspase-dependent cleavage. | 2009 Sep |
1 |
| 35 |
19546888 | Cbl negatively regulates JNK activation and cell death. | 2009 Aug |
1 |
| 36 |
18062779 | Phosphorylated ITIMs enable ubiquitylation of an inhibitory cell surface receptor. | 2008 Feb |
1 |
| 37 |
18235045 | Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. | 2008 Apr 1 |
1 |
| 38 |
18519587 | c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130. | 2008 Aug |
1 |
| 39 |
18663086 | Suppression of c-Cbl tyrosine phosphorylation inhibits neointimal formation in balloon-injured rat arteries. | 2008 Aug 12 |
1 |
| 40 |
17237826 | c-Cbl-facilitated cytoskeletal effects in v-Abl-transformed fibroblasts are regulated by membrane association of c-Cbl. | 2007 Jun 14 |
2 |
| 41 |
17255109 | Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation. | 2007 Mar 23 |
1 |
| 42 |
17372230 | A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis. | 2007 Mar 27 |
3 |
| 43 |
17635922 | Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase. | 2007 Sep 14 |
3 |
| 44 |
16289966 | Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav. | 2006 Aug |
4 |
| 45 |
16472699 | TC10 and insulin-stimulated glucose transport. | 2006 |
1 |
| 46 |
16479008 | Regulation of sprouty stability by Mnk1-dependent phosphorylation. | 2006 Mar |
2 |
| 47 |
16503409 | Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b and their regulation by Src kinases and CD45. | 2006 Mar-Apr |
2 |
| 48 |
16780420 | Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation. | 2006 Oct 1 |
1 |
| 49 |
16928382 | Enhanced ubiquitination of cytoskeletal proteins in pressure overloaded myocardium is accompanied by changes in specific E3 ligases. | 2006 Oct |
1 |
| 50 |
16969069 | Hypophosphorylation of residue Y1045 leads to defective downregulation of EGFRvIII. | 2006 Oct |
3 |