Glutathione

solute carrier family 7 member 11 ; Homo sapiens







132 Article(s)
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1 34741776 Interferon-γ induces retinal pigment epithelial cell Ferroptosis by a JAK1-2/STAT1/SLC7A11 signaling pathway in Age-related Macular Degeneration. 2022 Apr 1
2 34762602 15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation. 2022 Jan 4 2
3 35282646 Pan-Cancer Analyses Confirmed the Ferroptosis-Related Gene SLC7A11 as a Prognostic Biomarker for Cancer. 2022 4
4 35302125 Intelligent design of iron-doped LDH nanosheets for cooperative chemo-chemodynamic therapy of tumors. 2022 Apr 12 1
5 35337799 Monitoring the induction of ferroptosis following dissociation in human embryonic stem cells. 2022 May 2
6 35367340 Functional role of the SLC7A11-AS1/xCT axis in the development of gastric cancer cisplatin-resistance by a GSH-dependent mechanism. 2022 May 1 3
7 35447413 Hypoxia-induced HIF-1α/lncRNA-PMAN inhibits ferroptosis by promoting the cytoplasmic translocation of ELAVL1 in peritoneal dissemination from gastric cancer. 2022 Jun 2
8 35474100 Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia. 2022 Jun 1
9 35522946 The N6-methyladenosine modification enhances ferroptosis resistance through inhibiting SLC7A11 mRNA deadenylation in hepatoblastoma. 2022 May 2
10 35524288 Melatonin modulates Nrf2 activity to protect porcine pre-pubertal Sertoli cells from the abnormal H2 O2 generation and reductive stress effects of cadmium. 2022 May 6 1
11 35562334 N6-methyladenosine regulated FGFR4 attenuates ferroptotic cell death in recalcitrant HER2-positive breast cancer. 2022 May 13 1
12 35604883 N6 -methyladenosine-RNA methylation promotes expression of solute carrier family 7 member 11, an uptake transporter of cystine for lipid reactive oxygen species scavenger glutathione synthesis, leading to hepatoblastoma ferroptosis resistance. 2022 May 1
13 32699265 Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma. 2021 Feb 1
14 32749001 Cystine-glutamate antiporter xCT as a therapeutic target for cancer. 2021 Mar 2
15 32804006 Ferroptosis: machinery and regulation. 2021 Sep 1
16 33000412 Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy. 2021 Aug 2
17 33210459 Functional analysis of CD44 variants and xCT in canine tumours. 2021 Mar 1
18 33285240 Epidermal growth factor promotes glioblastoma cell death under glucose deprivation via upregulation of xCT (SLC7A11). 2021 Feb 1
19 33351681 Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition Are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms. 2021 Feb 1
20 33390474 [Anti-oxidants in astrocytes as target of neuroprotection for Parkinson's disease]. 2021 2
21 33401672 The Harmonious Interplay of Amino Acid and Monocarboxylate Transporters Induces the Robustness of Cancer Cells. 2021 Jan 2 2
22 33430127 Tumor-Associated Antigen xCT and Mutant-p53 as Molecular Targets for New Combinatorial Antitumor Strategies. 2021 Jan 8 1
23 33594332 Role of ferroptosis in the process of diabetes-induced endothelial dysfunction. 2021 Feb 15 1
24 33629335 Insights into the novel function of system Xc- in regulated cell death. 2021 Feb 4
25 33707434 mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation. 2021 Mar 11 1
26 33722571 PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer. 2021 Jun 1
27 33847044 Structure-Activity-Relationship-Aided Design and Synthesis of xCT Antiporter Inhibitors. 2021 Sep 6 1
28 33980655 Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition. 2021 Jul 1 1
29 34041026 The Activation of Endothelial Cells Relies on a Ferroptosis-Like Mechanism: Novel Perspectives in Management of Angiogenesis and Cancer Therapy. 2021 2
30 34074015 Mutant p53 Mediates Sensitivity to Cancer Treatment Agents in Oesophageal Adenocarcinoma Associated with MicroRNA and SLC7A11 Expression. 2021 May 24 1
31 34080411 Simple Fluorescence Assay for Cystine Uptake via the xCT in Cells Using Selenocystine and a Fluorescent Probe. 2021 Jun 25 1
32 34165166 Lycopene prevents oxygen-glucose deprivation-induced autophagic death in SH-SY5Y cells via inhibition of the oxidative stress-activated AMPK/mTOR pathway. 2021 Aug 1
33 34427100 SLC7A11 negatively associates with mismatch repair gene expression and endows glioblastoma cells sensitive to radiation under low glucose conditions. 2021 Nov 1
34 34445395 Glutathione and Related Molecules in Parkinsonism. 2021 Aug 13 3
35 34483935 Sulfasalazine Sensitizes Polyhematoporphyrin-Mediated Photodynamic Therapy in Cholangiocarcinoma by Targeting xCT. 2021 2
36 34571083 SLC7A11/ xCT is a target of miR-5096 and its restoration partially rescues miR-5096-mediated ferroptosis and anti-tumor effects in human breast cancer cells. 2021 Dec 1 2
37 34572286 Salubrinal Enhances Cancer Cell Death during Glucose Deprivation through the Upregulation of xCT and Mitochondrial Oxidative Stress. 2021 Aug 28 2
38 34623384 PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness. 2021 Dec 6 1
39 34630132 A-Lipoic Acid Alleviates Folic Acid-Induced Renal Damage Through Inhibition of Ferroptosis. 2021 2
40 34664408 YAP/TAZ and ATF4 drive resistance to Sorafenib in hepatocellular carcinoma by preventing ferroptosis. 2021 Dec 7 1
41 34768109 ABCC5 facilitates the acquired resistance of sorafenib through the inhibition of SLC7A11-induced ferroptosis in hepatocellular carcinoma. 2021 Dec 1
42 34785303 Downregulation of Cx43 reduces cisplatin-induced acute renal injury by inhibiting ferroptosis. 2021 Dec 1
43 31692172 Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT-targeted therapy. 2020 Jan 1
44 31761322 Efficacy of glutathione inhibitors for the treatment of ARID1A-deficient diffuse-type gastric cancers. 2020 Feb 5 4
45 31874187 Hydrogen peroxide triggers an increase in cell surface expression of system xc- in cultured human glioma cells. 2020 Mar 1
46 31914417 A synthetic lethal drug combination mimics glucose deprivation-induced cancer cell death in the presence of glucose. 2020 Jan 31 1
47 31931281 xCT (SLC7A11) expression confers intrinsic resistance to physical plasma treatment in tumor cells. 2020 Feb 2
48 32144264 Analysis of DNA methylation associates the cystine-glutamate antiporter SLC7A11 with risk of Parkinson's disease. 2020 Mar 6 1
49 32199332 Iron dyshomeostasis, lipid peroxidation and perturbed expression of cystine/glutamate antiporter in Alzheimer's disease: Evidence of ferroptosis. 2020 May 1
50 32312817 Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism. 2020 May 5 1