Glutathione

solute carrier family 7 member 11 ; Homo sapiens







132 Article(s)
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101 25687825 Loss of Nrf2 in bone marrow-derived macrophages impairs antigen-driven CD8(+) T cell function by limiting GSH and Cys availability. 2015 Jun 1
102 25745420 xCT, not just an amino-acid transporter: a multi-functional regulator of microbial infection and associated diseases. 2015 2
103 25985632 [Redox regulation in cancer stem cells]. 2015 May 1
104 26229077 Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype. 2015 Aug 18 1
105 23771433 xCT, component of cysteine/glutamate transporter, as an independent prognostic factor in human esophageal squamous cell carcinoma. 2014 May 1
106 24431147 The novel arsenical darinaparsin is transported by cystine importing systems. 2014 Apr 1
107 24686172 IGF-I regulates redox status in breast cancer cells by activating the amino acid transport molecule xC-. 2014 Apr 15 2
108 24708874 Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma. 2014 Apr 4 2
109 25002527 Nrf2- and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition. 2014 Sep 15 1
110 25009780 Redox status in mammalian cells and stem cells during culture in vitro: critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance. 2014 1
111 23334333 Redox regulation in stem-like cancer cells by CD44 variant isoforms. 2013 Oct 31 1
112 23357478 Extracellular cyclic GMP and its derivatives GMP and guanosine protect from oxidative glutamate toxicity. 2013 Apr 1
113 21409388 The oxidative stress-inducible cystine/glutamate antiporter, system x (c) (-) : cystine supplier and beyond. 2012 Jan 1
114 21111819 Reactive astrocytosis-induced perturbation of synaptic homeostasis is restored by nerve growth factor. 2011 Mar 2
115 21397861 CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth. 2011 Mar 8 2
116 21906871 Disruption of xCT inhibits cell growth via the ROS/autophagy pathway in hepatocellular carcinoma. 2011 Dec 15 2
117 20126446 Upregulation of xCT by KSHV-encoded microRNAs facilitates KSHV dissemination and persistence in an environment of oxidative stress. 2010 Jan 29 1
118 20551639 Downregulation of cystine transporter xc by irinotecan in human head and neck cancer FaDu xenografts. 2010 2
119 20858898 Hypoxia increases the dependence of glioma cells on glutathione. 2010 Nov 26 1
120 18992769 Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond. 2009 Jan 1
121 17615559 Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. 2008 Feb 1 1
122 17828297 The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death. 2008 Mar 6 1
123 18054200 xCT expression reduces the early cell cycle requirement for calcium signaling. 2008 Feb 1
124 18061179 A prominent role for mucosal cystine/cysteine metabolism in intestinal immunoregulation. 2008 Jan 1
125 17367118 Chemoinformatics analysis identifies cytotoxic compounds susceptible to chemoresistance mediated by glutathione and cystine/glutamate transport system xc-. 2007 Apr 19 3
126 17875604 Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin. 2007 Dec 1
127 18997287 Assessment of antioxidative activity of extract from fermented grain food mixture using chemical and cellular systems. 2007 1
128 19122795 Cellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegeneration. 2007 Jul 27 1
129 16103098 Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance. 2005 Aug 15 4
130 15450936 Biphasic induction of heme oxygenase-1 expression in macrophages stimulated with lipopolysaccharide. 2004 Nov 1 1
131 12498985 Vitamin C inhibits diethylmaleate-induced L-cystine transport in human vascular smooth muscle cells. 2003 Jan 1 1
132 11406111 Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells. 2001 Jun 6 1