| 1 |
35604094 | Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus. | 2022 May 23 |
5 |
| 2 |
32956624 | CRISPR-Cas9-Edited Tacrolimus-Resistant Antiviral T Cells for Advanced Adoptive Immunotherapy in Transplant Recipients. | 2021 Jan 6 |
1 |
| 3 |
33572801 | ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex. | 2021 Jan 29 |
1 |
| 4 |
34342774 | FK506-binding protein 2 (FKBP13) inhibit Bax-induced apoptosis in Saccharomyces cerevisiae (yeast). | 2021 Aug 3 |
2 |
| 5 |
34534579 | Saccharomyces cerevisiae Fpr1 functions as a chaperone to inhibit protein aggregation. | 2021 Nov 30 |
2 |
| 6 |
34662453 | Tacrolimus ameliorates podocyte injury by restoring FK506 binding protein 12 (FKBP12) at actin cytoskeleton. | 2021 Nov |
8 |
| 7 |
31955224 | Multiple genetic factors affecting the pharmacokinetic and pharmacodynamic processes of tacrolimus in Chinese myasthenia gravis patients. | 2020 May |
1 |
| 8 |
32192767 | FKBP12 dimerization mutations effect FK506 binding and differentially alter calcineurin inhibition in the human pathogen Aspergillus fumigatus. | 2020 May 21 |
4 |
| 9 |
32298692 | Rapamycin restrains platelet procoagulant responses via FKBP-mediated protection of mitochondrial integrity. | 2020 Jul |
1 |
| 10 |
32422433 | Regulation of the Ca2+-activated chloride channel Anoctamin-1 (TMEM16A) by Ca2+-induced interaction with FKBP12 and calcineurin. | 2020 Jul |
3 |
| 11 |
31321978 | Biosynthesis of Nonimmunosuppressive FK506 Analogues with Antifungal Activity. | 2019 Aug 23 |
6 |
| 12 |
29412644 | Conformational Entropy of FK506 Binding to FKBP12 Determined by Nuclear Magnetic Resonance Relaxation and Molecular Dynamics Simulations. | 2018 Mar 6 |
3 |
| 13 |
23676788 | Effectiveness of sirolimus in combination with cyclosporine against chronic rejection in a pediatric liver transplant patient. | 2013 |
1 |
| 14 |
23957229 | FK506-binding protein 12 ligands: a patent review. | 2013 Nov |
1 |
| 15 |
24303040 | Effect of Calstabin1 depletion on calcium transients and energy utilization in muscle fibers and treatment opportunities with RyR1 stabilizers. | 2013 |
2 |
| 16 |
19356587 | NMR solution structure of SlyD from Escherichia coli: spatial separation of prolyl isomerase and chaperone function. | 2009 Mar 27 |
1 |
| 17 |
19759356 | Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506). | 2009 Nov 26 |
6 |
| 18 |
19081378 | Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. | 2008 Dec 10 |
1 |
| 19 |
17524933 | An assay for the determination of sirolimus levels in the lymphocyte of transplant patients. | 2007 May |
1 |
| 20 |
16405911 | Structural characterization of the RyR1-FKBP12 interaction. | 2006 Mar 3 |
5 |
| 21 |
16720724 | FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor. | 2006 Jun |
2 |
| 22 |
15732051 | Non-FK506-binding protein-12 neuroimmunophilin ligands increase neurite elongation and accelerate nerve regeneration. | 2005 Apr 1 |
2 |
| 23 |
15745744 | Selective ligand purification using high-performance affinity beads. | 2005 Mar 15 |
1 |
| 24 |
16246307 | Mechanism of osteogenic induction by FK506 via BMP/Smad pathways. | 2005 Dec 16 |
5 |
| 25 |
14766396 | The immunophilin FKBP12: a molecular guardian of the TGF-beta family type I receptors. | 2004 Jan 1 |
1 |
| 26 |
15284440 | Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals. | 2004 Aug 17 |
1 |
| 27 |
14523907 | [Calcineurin inhibitors and mechanisms that are responsible for the appearance of post-transplant diabetes mellitus]. | 2003 Jul-Aug |
2 |
| 28 |
11520640 | Distribution of immunophilin FKBP-12 protein and mRNA within the mammalian cochlea and cochlear nucleus. | 2001 Sep |
1 |
| 29 |
10856121 | Effects of the immunosuppressant FK506 on intracellular Ca2+ release and Ca2+ accumulation mechanisms. | 2000 Jun 15 |
1 |
| 30 |
10051602 | Immunophilins, Refsum disease, and lupus nephritis: the peroxisomal enzyme phytanoyl-COA alpha-hydroxylase is a new FKBP-associated protein. | 1999 Mar 2 |
1 |
| 31 |
10336507 | Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506. | 1999 Jun |
2 |
| 32 |
10433096 | Autoantibodies to FK506 binding protein 12 (FKBP12) in autoimmune diseases. | 1999 |
1 |
| 33 |
9448137 | A tacrolimus-related immunosuppressant with biochemical properties distinct from those of tacrolimus. | 1998 Jan 15 |
3 |
| 34 |
9545268 | Effects of FK506-binding protein 12 and FK506 on autophosphorylation of epidermal growth factor receptor. | 1998 Apr 17 |
2 |
| 35 |
9145907 | Noncoplanar PCB 95 alters microsomal calcium transport by an immunophilin FKBP12-dependent mechanism. | 1997 May |
2 |
| 36 |
9346894 | FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain. | 1997 Oct 31 |
5 |
| 37 |
8680047 | Molecular mechanisms of new immunosuppressants. | 1996 Feb |
2 |
| 38 |
7533409 | Inhibition of insulin production by FK 506 is caused at the transcriptional level in pancreatic beta cell when FK BP-12 content is relatively high. | 1995 Feb |
1 |
| 39 |
7536825 | Neuronal regeneration enhances the expression of the immunophilin FKBP-12. | 1995 Apr |
1 |
| 40 |
7536932 | Activation of Ca2+ signaling in neutrophils by the mast cell-released immunophilin FKBP12. | 1995 Apr 11 |
3 |
| 41 |
7541038 | Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activity. | 1995 Jun 23 |
1 |
| 42 |
7510077 | Immunophilin receptors for immunosuppressive drugs. | 1993 Dec |
1 |
| 43 |
7678400 | Structure-activity profiles of macrolactam immunosuppressant FK-506 analogues. | 1993 Jan 25 |
1 |
| 44 |
7678431 | Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin. | 1993 Jan 5 |
2 |
| 45 |
7684380 | FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818. | 1993 May 25 |
1 |
| 46 |
1374404 | FK506 binding protein associated with the calcium release channel (ryanodine receptor). | 1992 May 15 |
2 |
| 47 |
1375189 | FKBP-12 is not an inhibitor of protein kinase C. | 1992 Jun |
1 |
| 48 |
1713687 | Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. | 1991 Aug 1 |
2 |
| 49 |
1719972 | FKBP, the binding protein for the immunosuppressive drug, FK-506, is not an inhibitor of protein kinase C activity. | 1991 Oct 31 |
1 |
| 50 |
1930186 | Chromosomal assignment of the human immunophilin FKBP-12 gene. | 1991 Sep 30 |
1 |