Title : Effect of Calstabin1 depletion on calcium transients and energy utilization in muscle fibers and treatment opportunities with RyR1 stabilizers.

Pub. Date : 2013

PMID : 24303040






2 Functional Relationships(s)
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1 We found that depletion of calstabin1 with the calstabin1-dissociation compound FK506 increased the release of calcium from the SR by 14 % during tetanic stimulation (50 Hz, 300 ms) and delayed cytosolic calcium removal. Tacrolimus FKBP prolyl isomerase 1A Homo sapiens
2 We found that depletion of calstabin1 with the calstabin1-dissociation compound FK506 increased the release of calcium from the SR by 14 % during tetanic stimulation (50 Hz, 300 ms) and delayed cytosolic calcium removal. Tacrolimus FKBP prolyl isomerase 1A Homo sapiens