Tyrosine

interleukin 2 ; Homo sapiens







192 Article(s)
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1 35192696 A novel intramolecular negative regulation of mouse Jak3 activity by tyrosine 820. 2022 Jun 4 1
2 31935623 Recent advancements in the treatment of metastatic clear cell renal cell carcinoma: A review of the evidence using second-generation p-values. 2020 Jan 3 5
3 32072341 Novel Hemizygous IL2RG p.(Pro58Ser) Mutation Impairs IL-2 Receptor Complex Expression on Lymphocytes Causing X-Linked Combined Immunodeficiency. 2020 Apr 3
4 32469452 PTPN22 interacts with EB1 to regulate T-cell receptor signaling. 2020 Jul 1
5 30460991 A sequence conserved between CD5 and CD6 binds an FERM domain and exerts a restraint on T-cell activation. 2019 Mar 1
6 31085588 CD25 and Protein Phosphatase 2A Cooperate to Enhance IL-2R Signaling in Human Regulatory T Cells. 2019 Jul 1 1
7 32038633 Interleukin-2-Inducible T-Cell Kinase Deficiency Impairs Early Pulmonary Protection Against Mycobacterium tuberculosis Infection. 2019 1
8 30455079 Vitamin D pathway activation selectively deactivates signal transducer and activator of transcription (STAT) proteins and inflammatory cytokine production in natural killer leukemic large granular lymphocytes. 2018 Nov 2
9 27153543 Defective STAT1 activation associated with impaired IFN-γ production in NK and T lymphocytes from metastatic melanoma patients treated with IL-2. 2016 Jun 14 1
10 27936140 Time-Dependent Regulation of IL-2R α-Chain (CD25) Expression by TCR Signal Strength and IL-2-Induced STAT5 Signaling in Activated Human Blood T Lymphocytes. 2016 1
11 26425665 SILAC-based quantification of changes in protein tyrosine phosphorylation induced by Interleukin-2 (IL-2) and IL-15 in T-lymphocytes. 2015 Dec 2
12 24850725 Signal transduction by different forms of the γδ T cell-specific pattern recognition receptor WC1. 2014 Jul 1 1
13 23341462 Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex. 2013 Mar 8 1
14 25509109 [The STAT5 signaling in the expression of alpha-subunit of interleukin-2 receptor in human blood lymphocytes]. 2013 1
15 22116305 Molecular mechanism of interleukin-2-induced mucosal homeostasis. 2012 Mar 1 1
16 22402124 JAK-STAT and JAK-PI3K-mTORC1 pathways regulate telomerase transcriptionally and posttranslationally in ATL cells. 2012 May 2
17 22646506 Protein phosphatase 1 is involved in IL-2-induced IL-5 and IL-13 expression in human T cells. 2012 Jul 1
18 21722762 Interleukin-2 signaling pathway analysis by quantitative phosphoproteomics. 2011 Dec 10 5
19 19923221 Protein phosphatase 2A regulates interleukin-2 receptor complex formation and JAK3/STAT5 activation. 2010 Feb 5 3
20 17846080 Constitutive nuclear import of latent and activated STAT5a by its coiled coil domain. 2008 Feb 1
21 18463202 T-cell receptor/CD28-mediated activation of human T lymphocytes induces expression of functional mu-opioid receptors. 2008 Aug 1
22 17178161 Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells. 2007 Mar 1
23 17537734 Janus kinase 3 regulates interleukin 2-induced mucosal wound repair through tyrosine phosphorylation of villin. 2007 Oct 19 2
24 17640867 Leupaxin negatively regulates B cell receptor signaling. 2007 Sep 14 1
25 16517754 Sensitization of IL-2 signaling through TLR-7 enhances B lymphoma cell immunogenicity. 2006 Mar 15 1
26 16762027 Interleukin-4 supports interleukin-12-induced proliferation and interferon-gamma secretion in human activated lymphoblasts and T helper type 1 cells. 2006 Sep 1
27 16782030 HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse. 2006 Jun 1
28 15814281 Daclizumab therapy in kidney transplantation-different mechanisms of action in- versus ex-vivo? 2005 Mar 1
29 15121872 Tyrosine 813 is a site of JAK2 autophosphorylation critical for activation of JAK2 by SH2-B beta. 2004 May 2
30 15170389 Interaction of the tyrosine phosphatase SHP-2 with Gab2 regulates Rho-dependent activation of the c-fos serum response element by interleukin-2. 2004 Sep 1 3
31 15302845 Qualitatively differential regulation of T cell activation and apoptosis by T cell receptor zeta chain ITAMs and their tyrosine residues. 2004 Sep 1
32 15356145 Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation. 2004 Sep 15 1
33 12525482 Anti-apoptotic signaling by the interleukin-2 receptor reveals a function for cytoplasmic tyrosine residues within the common gamma (gamma c) receptor subunit. 2003 Mar 21 1
34 11781254 Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin. 2002 Jan 15 2
35 11792427 Role for adapter proteins in costimulatory signals of CD2 and IL-2 on NK cell activation. 2002 Jan 1
36 11856346 GPI-microdomains (membrane rafts) and signaling of the multi-chain interleukin-2 receptor in human lymphoma/leukemia T cell lines. 2002 Feb 1
37 12101281 Differential localization of IL-2- and -15 receptor chains in membrane rafts of human T cells. 2002 Jul 1
38 12543077 SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells. 2002 Nov 24 1
39 11145913 Herpesvirus saimiri oncoproteins Tip and StpC synergistically stimulate NF-kappaB activity and interleukin-2 gene expression. 2001 Jan 5 1
40 11238664 Functional IL-2 receptor beta (CD122) and gamma (CD132) chains are expressed by fibroblast-like synoviocytes: activation by IL-2 stimulates monocyte chemoattractant protein-1 production. 2001 Mar 15 1
41 11260071 Rapid protein-based assays for the diagnosis of T-B+ severe combined immunodeficiency. 2001 Mar 1
42 11331873 Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras. 2001 May 3
43 11340297 Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a. 2001 5
44 11468191 Defective expression of the interleukin-2/interleukin-15 receptor beta subunit leads to a natural killer cell-deficient form of severe combined immunodeficiency. 2001 Aug 1 1
45 11513540 Detection of intracellular phosphorylated STAT-4 by flow cytometry. 2001 Sep 1
46 11535532 The deubiquitinating enzyme DUB-2 prolongs cytokine-induced signal transducers and activators of transcription activation and suppresses apoptosis following cytokine withdrawal. 2001 Sep 15 2
47 10602027 Association of STAT1, STAT3 and STAT5 proteins with the IL-2 receptor involves different subdomains of the IL-2 receptor beta chain. 2000 Jan 1
48 10604984 Cutting edge: tyrosine-independent transmission of inhibitory signals by CTLA-4. 2000 Jan 1 1
49 10604992 The inhibitory function of CTLA-4 does not require its tyrosine phosphorylation. 2000 Jan 1 1
50 10617656 Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation. 2000 Jan 7 1