Tyrosine

interleukin 2 ; Homo sapiens







192 Article(s)
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51 10779760 IL-2 signaling in human monocytes involves the phosphorylation and activation of p59hck. 2000 May 1 2
52 10849438 Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription. 2000 Jun 16 1
53 10859484 Interleukin-2: structural and biological relatedness to opioid peptides. 2000 1
54 10867021 Protein-tyrosine kinase Pyk2 is involved in interleukin-2 production by Jurkat T cells via its tyrosine 402. 2000 Jun 30 1
55 10898517 Two YxxL segments of a single immunoreceptor tyrosine-based activation motif in the CD3zeta molecule differentially activate calcium mobilization and mitogen-activated protein kinase family pathways. 2000 Jun 1
56 10920190 Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids. 2000 Aug 15 1
57 11034377 Galectin-1 induces partial TCR zeta-chain phosphorylation and antagonizes processive TCR signal transduction. 2000 Oct 1 1
58 11097834 Thrombopoietin and interleukin-2 induce association of CRK with STAT5. 2000 Nov 19 2
59 11147695 Daclizumab (Zenapax) inhibits early interleukin-2 receptor signal transduction events. 2000 Nov 5
60 12110904 Interaction between Jak3 and Nucleosome Assembly Protein 1. 2000 1
61 9886399 IL-2 induces STAT4 activation in primary NK cells and NK cell lines, but not in T cells. 1999 Jan 1 1
62 9915850 CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28. 1999 Jan 29 1
63 9973378 IL-4 selectively inhibits IL-2-triggered Stat5 activation, but not proliferation, in human T cells. 1999 Feb 1 1
64 10088663 Defective IL2 gene expression in newborn is accompanied with impaired tyrosine-phosphorylation in T cells. 1999 Mar 2
65 10090941 Downregulation of JAK3 protein levels in T lymphocytes by prostaglandin E2 and other cyclic adenosine monophosphate-elevating agents: impact on interleukin-2 receptor signaling pathway. 1999 Apr 1 1
66 10201984 The functional synergy between IL-12 and IL-2 involves p38 mitogen-activated protein kinase and is associated with the augmentation of STAT serine phosphorylation. 1999 Apr 15 1
67 10369681 Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization. 1999 Jun 15 1
68 10373416 CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells. 1999 Jun 25 1
69 10373548 SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation. 1999 Jul 4
70 10400642 Role of protein kinase C in signal attenuation following T cell receptor engagement. 1999 Jul 16 1
71 10409671 FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells. 1999 Jul 23 1
72 10421845 Critical role of the membrane-proximal, proline-rich motif of the interleukin-2 receptor gammac chain in the Jak3-independent signal transduction. 1999 Jun 1
73 10438903 Cutting edge: TCR stimulation by antibody and bacterial superantigen induces Stat3 activation in human T cells. 1999 Aug 15 1
74 9461587 Interleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cells. 1998 Feb 13 5
75 9494076 Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK. 1998 Mar 15 2
76 9520455 Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells. 1998 Mar 31 3
77 9613985 Suppression of proliferation and phosphorylation of Jak3 and STAT5 in malignant T-cell lymphoma cells by derivatives of octylamino-undecyl-dimethylxanthine. 1998 Feb 1
78 9618521 Interleukin-2 induces beta2-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB). 1998 Jun 9 5
79 9660791 A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes. 1998 Jul 17 1
80 9749527 Induction of late activation events by Igbeta signaling subunit of B-cell receptor in Jurkat T-cell without tyrosine phosphorylation. 1998 Aug 31 1
81 9785040 The molecular basis for bidirectional communication between the immune and neuroendocrine systems. 1998 Sep 4
82 9811525 Interleukin 2 and 15 activate Stat3alpha in human T lymphocytes. 1998 Oct 1
83 8978277 Erythropoietin activates Raf1 by an Shc-independent pathway in CTLL-EPO-R cells. 1997 Jan 1 2
84 9098929 Interleukin 2 induces a transient downregulation of protein phosphatase 1 and 2A activity in human T cells. 1997 Mar 2
85 9115214 Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases. 1997 May 2 1
86 9129156 Interleukin-2 induces tyrosine phosphorylation of SHP-2 through IL-2 receptor beta chain. 1997 Apr 3 6
87 9162019 Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation. 1997 May 30 2
88 9182578 Two discrete regions of interleukin-2 (IL2) receptor beta independently mediate IL2 activation of a PD98059/rapamycin/wortmannin-insensitive Stat5a/b serine kinase. 1997 Jun 13 2
89 9200453 TGF-beta inhibits IL-2-induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes. 1997 Jul 1 3
90 9278318 The Lck SH2 phosphotyrosine binding site is critical for efficient TCR-induced processive tyrosine phosphorylation of the zeta-chain and IL-2 production. 1997 Sep 1 2
91 9295038 Functional analysis of immunoreceptor tyrosine-based activation motif (ITAM)-mediated signal transduction: the two YxxL segments within a single CD3zeta-ITAM are functionally distinct. 1997 Aug 1
92 9305919 STAT3 is a serine kinase target in T lymphocytes. Interleukin 2 and T cell antigen receptor signals converge upon serine 727. 1997 Sep 26 2
93 9326745 A selective impairment of the IL-2 system in lymphocytes of patients with glioblastomas: increased level of soluble IL-2R and reduced protein tyrosine phosphorylation. 1997 Jan-Feb 2
94 9354668 Structural and functional basis for JAK3-deficient severe combined immunodeficiency. 1997 Nov 15 2
95 9357823 Epithelial cell kinase-B61: an autocrine loop modulating intestinal epithelial migration and barrier function. 1997 Oct 1
96 9371209 Selective inhibition of T cell proliferation but not expression of effector function by human alveolar macrophages. 1997 Sep 1
97 9382798 Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation. 1997 Nov 1 1
98 9398404 IL-2 and IL-7 induce heterodimerization of STAT5 isoforms in human peripheral blood T lymphoblasts. 1997 Nov 1 1
99 9407053 Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth. 1997 Dec 26 1
100 8551221 CD16-mediated p21ras activation is associated with Shc and p36 tyrosine phosphorylation and their binding with Grb2 in human natural killer cells. 1996 Jan 1 1