Clarithromycin

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







93 Article(s)
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51 20735423 Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro. 2010 Sep 1
52 20837591 Fatal hydrocodone overdose in a child: pharmacogenetics and drug interactions. 2010 Oct 1
53 19261952 Evaluation of potential interaction between vinorelbine and clarithromycin. 2009 Mar 1
54 19414584 Modeling the autoinhibition of clarithromycin metabolism during repeated oral administration. 2009 Jul 3
55 19457725 Simultaneous determination of clarithromycin, rifampicin and their main metabolites in human plasma by liquid chromatography-tandem mass spectrometry. 2009 Jun 15 1
56 19701237 Evaluation of CYP3A activity in humans using three different parameters based on endogenous cortisol metabolism. 2009 Sep 1
57 17635500 Interaction between midazolam and clarithromycin in the elderly. 2008 Jan 2
58 18558792 Risk management of simvastatin or atorvastatin interactions with CYP3A4 inhibitors. 2008 1
59 19122337 Effect of clarithromycin on the pharmacokinetics of pranlukast in healthy volunteers. 2008 1
60 17381388 Simvastatin-associated rhabdomyolysis after coadministration of macrolide antibiotics in two patients. 2007 Apr 1
61 17484517 Drug-drug interactions in the metabolism of imidafenacin: role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymes. 2007 Feb 1
62 17695796 [Measurement of rifampicin and clarithromycin in serum by high-performance liquid chromatography with electrochemical detection]. 2007 Jul 3
63 18033049 [Carbamazepine and clarithromycin: a clinically relevant drug interaction]. 2007 Nov 1
64 16372380 The effect of ciprofloxacin and clarithromycin on sildenafil oral bioavailability in human volunteers. 2006 Mar 3
65 16410677 Effect of clarithromycin on the pharmacokinetics of cabergoline in healthy controls and in patients with Parkinson's disease. 2006 Jan 1
66 16416302 Quantitative prediction of macrolide drug-drug interaction potential from in vitro studies using testosterone as the human cytochrome P4503A substrate. 2006 Mar 1
67 15735612 Inhibition of human intestinal wall metabolism by macrolide antibiotics: effect of clarithromycin on cytochrome P450 3A4/5 activity and expression. 2005 Mar 3
68 15752376 Effects of clarithromycin on lansoprazole pharmacokinetics between CYP2C19 genotypes. 2005 Mar 2
69 15856433 Effect of clarithromycin on the enantioselective disposition of lansoprazole in relation to CYP2C19 genotypes. 2005 Jun 2
70 14715050 Pharmacokinetic factors in the adverse cardiovascular effects of antipsychotic drugs. 2004 1
71 15058617 Drug interactions in dentistry: the importance of knowing your CYPs. 2004 Mar 2
72 12949438 Inhibition of cytochrome P450 3A: relevant drug interactions in gastroenterology. 2003 1
73 14570755 Evidence for the validity of cortisol 6 beta-hydroxylation clearance as a new index for in vivo cytochrome P450 3A phenotyping in humans. 2003 Nov 2
74 15618724 CYP isoforms involved in the metabolism of clarithromycin in vitro: comparison between the identification from disappearance rate and that from formation rate of metabolites. 2003 4
75 11197581 Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin. 2001 Jan 1
76 11322176 Effect of clarithromycin and itraconazole on the pharmacokinetics of ropivacaine. 2001 Apr 1
77 11408986 Effect of levofloxacin on theophylline clearance during theophylline and clarithromycin combination therapy. 2001 Jun 1
78 11836874 [Safety profile of statins]. 2001 Nov 1
79 10668858 Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition. 2000 Jan 1
80 10722500 Pharmacokinetic interaction between amprenavir and clarithromycin in healthy male volunteers. 2000 Apr 1
81 10923859 Identification of enzymes responsible for rifalazil metabolism in human liver microsomes. 2000 Jun 1
82 10926350 Drug interactions with cisapride: clinical implications. 2000 Jul 1
83 10950845 An in vitro model for predicting in vivo inhibition of cytochrome P450 3A4 by metabolic intermediate complex formation. 2000 Sep 5
84 11012550 Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin. 2000 Oct 1
85 9951426 Effect of clarithromycin on the pharmacokinetics and pharmacodynamics of pimozide in healthy poor and extensive metabolizers of cytochrome P450 2D6 (CYP2D6). 1999 Jan 3
86 9972380 Torsade de pointes induced by cisapride/clarithromycin interaction. 1999 Jan 1
87 10383920 An in vitro study on the metabolism and possible drug interactions of rokitamycin, a macrolide antibiotic, using human liver microsomes. 1999 Jul 1
88 10511062 Effects of clarithromycin on the metabolism of omeprazole in relation to CYP2C19 genotype status in humans. 1999 Sep 1
89 10589373 Clinical pharmacokinetics of clarithromycin. 1999 Nov 3
90 10600094 Potential interaction between itraconazole and clarithromycin. 1999 Dec 1
91 9640482 Syncopal episodes associated with cisapride and concurrent drugs. 1998 Jun 2
92 9728893 The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin. 1998 Aug 2
93 9131953 The mechanism of cyclosporine toxicity induced by clarithromycin. 1997 Feb 3