Clarithromycin

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







93 Article(s)
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1 35579824 Prediction of Drug-Drug Interactions After Esketamine Intranasal Administration Using a Physiologically Based Pharmacokinetic Model. 2022 May 17 1
2 35616006 Pharmacokinetics of asciminib in the presence of CYP3A or P-gp inhibitors, CYP3A inducers, and acid-reducing agents. 2022 May 26 1
3 33348240 The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects. 2021 Feb 4
4 33991350 Population Pharmacokinetic Analysis of Bedaquiline-Clarithromycin for Dose Selection Against Pulmonary Nontuberculous Mycobacteria Based on a Phase 1, Randomized, Pharmacokinetic Study. 2021 Oct 2
5 34467456 Evidence-Based Guidelines for Drug Interaction Studies: Model-Informed Time Course of Intestinal and Hepatic CYP3A4 Inhibition by Clarithromycin. 2021 Aug 31 6
6 34619548 Reduced theophylline clearance due to hepatic congestion secondary to right heart failure - A population pharmacokinetic study. 2021 Dec 1
7 31628882 Interaction potential between clarithromycin and individual statins-A systematic review. 2020 Apr 1
8 32274687 Evidence of Clinically Meaningful Drug-Drug Interaction With Concomitant Use of Colchicine and Clarithromycin. 2020 Jul 1
9 32967779 Applications of a grid-based CYP3A4 Template system to understand the interacting mechanisms of large-size ligands; part 4 of CYP3A4 Template study. 2020 Dec 1
10 30898762 Role of CYP3A4 in bone marrow microenvironment-mediated protection of FLT3/ITD AML from tyrosine kinase inhibitors. 2019 Mar 26 1
11 30920135 Regulation of drug metabolizing enzymes in the leukaemic bone marrow microenvironment. 2019 Jun 2
12 31656654 Effect of rifampicin and clarithromycin on the CYP3A activity in patients with Mycobacterium avium complex. 2019 Sep 2
13 30178440 The influences of CYP2C9*1/*3 genotype on the pharmacokinetics of zolpidem. 2018 Sep 4
14 27822600 Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication Regimens. 2017 Jan 1
15 27928738 Effect of Multiple Oral Doses of the Potent CYP3A4 Inhibitor Clarithromycin on the Pharmacokinetics of a Single Oral Dose of Vonoprazan: A Phase I, Open-Label, Sequential Design Study. 2017 Mar 2
16 28674358 Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole. 2017 2
17 26668209 Evaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug Transporters. 2016 Mar 1
18 27236320 Dose-Dependent Bioavailability and CYP3A Inhibition Contribute to Non-Linear Pharmacokinetics of Voriconazole. 2016 Dec 1
19 25429094 Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. 2015 Feb 1
20 25534598 Risk of adverse events among older adults following co-prescription of clarithromycin and statins not metabolized by cytochrome P450 3A4. 2015 Feb 17 3
21 25915157 Human bone marrow niche chemoprotection mediated by cytochrome P450 enzymes. 2015 Jun 20 1
22 25976224 The enhancement of cardiac toxicity by concomitant administration of Berberine and macrolides. 2015 Aug 30 1
23 26497728 A population-based analysis of the risk of drug interaction between clarithromycin and statins for hospitalisation or death. 2015 Oct 24 1
24 26819743 Serum concentrations of clarithromycin and rifampicin in pulmonary Mycobacterium avium complex disease: long-term changes due to drug interactions and their association with clinical outcomes. 2015 4
25 23738582 Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers. 2014 Jan 1
26 24035278 Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. 2014 Mar 3
27 25041770 Rhabdomyolysis in association with simvastatin and dosage increment in clarithromycin. 2014 Jul 2
28 25106415 Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1. 2014 Nov 2
29 25359648 Vitamin and mineral supplements: friend or foe when combined with medications? 2014 Nov 1
30 25571290 A pharmacokinetic drug-drug interaction model of simvastatin and clarithromycin in humans. 2014 1
31 22777148 Rate of onset of inhibition of gut-wall and hepatic CYP3A by clarithromycin. 2013 Mar 7
32 23462027 Colchicine-antimicrobial drug interactions: what pharmacists need to know in treating gout. 2013 Mar 1
33 23514827 Mechanism-based inhibition profiles of erythromycin and clarithromycin with cytochrome P450 3A4 genetic variants. 2013 3
34 23778904 Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. 2013 Jun 18 4
35 23847265 Comparing two types of macrolide antibiotics for the purpose of assessing population-based drug interactions. 2013 1
36 24252529 [Pharmacokinetic interactions]. 2013 Jun 1
37 24346990 Calcium-channel blocker-clarithromycin drug interactions and acute kidney injury. 2013 Dec 18 1
38 25011542 Retrospective analysis of severe neutropenia in patients receiving concomitant administration of docetaxel and clarithromycin. 2013 1
39 22170330 Clarithromycin is absorbed by an intestinal uptake mechanism that is sensitive to major inhibition by rifampicin: results of a short-term drug interaction study in foals. 2012 Mar 2
40 22372724 Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control study. 2012 Mar 1 1
41 22644980 Risk of hypotension with concomitant use of calcium-channel blockers and macrolide antibiotics. 2012 Jun 15 1
42 28520375 Aripiprazole Therapy and CYP2D6 Genotype 2012 1
43 21242274 The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers. 2011 Feb 22 1
44 21480191 Novel evidence-based colchicine dose-reduction algorithm to predict and prevent colchicine toxicity in the presence of cytochrome P450 3A4/P-glycoprotein inhibitors. 2011 Aug 1
45 22009620 The difficulties of polytherapy: examples from antimicrobial chemotherapy. 2011 Oct 2
46 19884323 Physiologically based pharmacokinetic model of mechanism-based inhibition of CYP3A by clarithromycin. 2010 Feb 9
47 19897389 Clarithromycin, a potent inhibitor of CYP3A, greatly increases exposure to oral S-ketamine. 2010 Jul 3
48 19943026 [Interactions with antiretroviral drugs]. 2010 Jan 1
49 20305307 [Complex hallucination (visual-auditory) during coadministration of tramadol and clarithromycin]. 2010 Mar 1
50 20446912 Assessment of competitive and mechanism-based inhibition by clarithromycin: use of domperidone as a CYP3A probe-drug substrate and various enzymatic sources including a new cell-based assay with freshly isolated human hepatocytes. 2010 Apr 2