Pub. Date : 2017 Mar
PMID : 27928738
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Effect of Multiple Oral Doses of the Potent CYP3A4 Inhibitor Clarithromycin on the Pharmacokinetics of a Single Oral Dose of Vonoprazan: A Phase I, Open-Label, Sequential Design Study. | Clarithromycin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
2 | CONCLUSIONS: Modest increases in plasma concentrations of the potent CYP3A4 inhibitor clarithromycin and vonoprazan were observed during coadministration, however these differences were not considered clinically significant. | Clarithromycin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |