Glucosylceramides

UDP-glucose ceramide glucosyltransferase ; Mus musculus







20 Article(s)
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Pub. Year
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1 35188773 Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore. 2022 Mar 10 1
2 34509608 A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy. 2021 Nov 2
3 34686711 Preclinical pharmacology of glucosylceramide synthase inhibitor venglustat in a GBA-related synucleinopathy model. 2021 Oct 22 1
4 31208914 Substrate Reduction Therapy for Sandhoff Disease through Inhibition of Glucosylceramide Synthase Activity. 2019 Aug 7 1
5 31265321 Role of Glucosylceramide in Lung Endothelial Cell Fate and Emphysema. 2019 Nov 1 4
6 33654788 Fluorescence HPLC Analysis of the in-vivo Activity of Glucosylceramide Synthase. 2019 Jun 20 1
7 28223512 Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models. 2017 Mar 7 1
8 28490444 Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury. 2017 Jul 1
9 26483191 Amyotrophic lateral sclerosis and denervation alter sphingolipids and up-regulate glucosylceramide synthase. 2015 Dec 20 2
10 24977484 PS dependent APP cleavage regulates glucosylceramide synthase and is affected in Alzheimer's disease. 2014 1
11 25551612 Ubiquitous transgene expression of the glucosylceramide-synthesizing enzyme accelerates glucosylceramide accumulation and storage cells in a Gaucher disease mouse model. 2014 1
12 23473748 Cell-specific in vivo functions of glycosphingolipids: lessons from genetic deletions of enzymes involved in glycosphingolipid synthesis. 2013 Apr 2
13 23555901 ARF6 regulates neuron differentiation through glucosylceramide synthase. 2013 2
14 21325339 Ceramide glucosyltransferase of the nematode Caenorhabditis elegans is involved in oocyte formation and in early embryonic cell division. 2011 Jun 3
15 21738789 Iminosugar-based inhibitors of glucosylceramide synthase increase brain glycosphingolipids and survival in a mouse model of Sandhoff disease. 2011 1
16 20432257 Hepatic glycosphingolipid deficiency and liver function in mice. 2010 May 2
17 16109770 Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth. 2005 Aug 30 1
18 12692077 The absence of functional glucosylceramide synthase does not sensitize melanoma cells for anticancer drugs. 2003 Jun 3
19 12417405 Early developmental expression of the gene encoding glucosylceramide synthase, the enzyme controlling the first committed step of glycosphingolipid synthesis. 2002 Dec 19 1
20 9623774 Molecular cloning and expression of mouse ceramide glucosyltransferase. 1998 May 2