Title : A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy.

Pub. Date : 2021 Nov

PMID : 34509608






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The glycosphingolipid GlcCer is synthesized by a single enzyme, glucosylceramide synthase (GCS), and small molecule inhibitors (GCSi) reduce cellular glycosphingolipid levels. Glucosylceramides UDP-glucose ceramide glucosyltransferase Mus musculus
2 The glycosphingolipid GlcCer is synthesized by a single enzyme, glucosylceramide synthase (GCS), and small molecule inhibitors (GCSi) reduce cellular glycosphingolipid levels. Glucosylceramides UDP-glucose ceramide glucosyltransferase Mus musculus