Guanosine Triphosphate

RAS like proto-oncogene A ; Homo sapiens







63 Article(s)
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Pub. Year
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1 34074494 The RAL signaling network: Cancer and beyond. 2021 1
2 34767674 Dysregulation of RalA signaling through dual regulatory mechanisms exerts its oncogenic functions in hepatocellular carcinoma. 2021 Nov 12 1
3 31916136 NMR resonance assignments for the active and inactive conformations of the small G protein RalA. 2020 Apr 2
4 30500825 De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay. 2018 Nov 2
5 28744424 Single-molecule fluorescence imaging of RalGDS on cell surfaces during signal transduction from Ras to Ral. 2017 2
6 26477566 Agonist-induced changes in RalA activities allows the prediction of the endocytosis of G protein-coupled receptors. 2016 Jan 3
7 27334922 Inhibition of Ral GTPases Using a Stapled Peptide Approach. 2016 Aug 26 2
8 27773821 Tyrosine phosphorylation of RalGDS by c-Met receptor blocks its interaction with Ras. 2016 Nov 18 3
9 25213293 RLIP76 blockade by siRNA inhibits proliferation, enhances apoptosis, and suppresses invasion in HT29 colon cancer cells. 2015 Mar 1
10 26033452 Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer. 2015 May 30 1
11 26158537 TD-60 links RalA GTPase function to the CPC in mitosis. 2015 Jul 9 1
12 26425463 Pleiotropic effects of statins. 2015 Sep-Oct 1
13 25103239 A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes. 2014 Oct 1 1
14 25169936 Platelets are highly activated in patients of chronic thromboembolic pulmonary hypertension. 2014 Nov 1
15 25431955 An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities. 2014 Nov 15 1
16 22700969 RalA and RalB proteins are ubiquitinated GTPases, and ubiquitinated RalA increases lipid raft exposure at the plasma membrane. 2012 Aug 24 2
17 23226417 Identification and characterisation of the RalA-ERp57 interaction: evidence for GDI activity of ERp57. 2012 1
18 21148297 A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action. 2011 Jan 1 1
19 21235523 Cell polarity during motile processes: keeping on track with the exocyst complex. 2011 Feb 1 1
20 21242975 Cyclin D1 interacts and collaborates with Ral GTPases enhancing cell detachment and motility. 2011 Apr 21 2
21 21494904 Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a. 2011 Apr 3
22 20145037 Sec5 and Exo84 foster oncogenic ras-mediated tumorigenesis. 2010 Feb 2
23 20562921 Ral activation promotes melanomagenesis. 2010 Aug 26 2
24 20603646 Proto-oncogenic H-Ras, K-Ras, and N-Ras are involved in muscle differentiation via phosphatidylinositol 3-kinase. 2010 Aug 1
25 17938170 Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway. 2008 Jan 4 2
26 18417737 Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells. 2008 Jul 1 1
27 18948269 RalA functions as an indispensable signal mediator for the nutrient-sensing system. 2008 Dec 12 1
28 16757319 Biochemical and biological analyses of Rgr RalGEF oncogene. 2006 3
29 15592429 RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity. 2005 Jan 12 2
30 15130921 Small GTP-binding protein Ral is involved in cAMP-mediated release of von Willebrand factor from endothelial cells. 2004 Jul 3
31 15470141 Ral and phospholipase D2-dependent pathway for constitutive metabotropic glutamate receptor endocytosis. 2004 Oct 6 1
32 12839989 Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex. 2003 Jul 1 2
33 11744922 The exocyst complex binds the small GTPase RalA to mediate filopodia formation. 2002 Jan 1
34 11861368 The role of Ral A in epidermal growth factor receptor-regulated cell motility. 2002 Feb 15 1
35 12067705 A role for calcium in sphingosine 1-phosphate-induced phospholipase D activity in C2C12 myoblasts. 2002 Jun 19 1
36 12526085 Phosphorylation of 46-kDa protein of synaptic vesicle membranes is stimulated by GTP and Ca2+/calmodulin. 2002 Dec 31 1
37 11322487 Regulation of GTP-binding state in RalA through Ca2+ and calmodulin. 2001 Mar 31 7
38 11397694 Small GTP-binding protein Ral modulates regulated exocytosis of von Willebrand factor by endothelial cells. 2001 Jun 3
39 11406615 The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene. 2001 Aug 10 2
40 10747847 Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral. 2000 May 5 1
41 10851075 The Rgr oncogene (homologous to RalGDS) induces transformation and gene expression by activating Ras, Ral and Rho mediated pathways. 2000 May 25 1
42 10861233 Low-density lipoprotein activates the small GTPases Rap1 and Ral in human platelets. 2000 Jul 1 1
43 11455956 Structure characterization of human RalGDS gene, and the identification of its novel variant. 2000 1
44 10329639 Ca2+/calmodulin stimulates GTP binding to the ras-related protein ral-A. 1999 May 21 2
45 10364219 Effector recognition by the small GTP-binding proteins Ras and Ral. 1999 Jun 18 4
46 10494784 Small GTP-binding protein RalA associates with Weibel-Palade bodies in endothelial cells. 1999 Sep 2
47 10512754 Dissociation of RalA from synaptic membranes by Ca2+/calmodulin. 1999 Oct 5 3
48 9550702 Ras-dependent activation of the small GTPase Ral. 1998 Apr 9 3
49 9688545 Activation of phospholipase D1 by direct interaction with ADP-ribosylation factor 1 and RalA. 1998 Jul 3 1
50 9843482 All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral. 1998 Dec 1 1