Title : Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway.

Pub. Date : 2008 Jan 4

PMID : 17938170






2 Functional Relationships(s)
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1 This secretion was inhibited by the addition of GTP-Ral-binding domain (RBD) of Sec5, which is a component of the exocyst complex known to function as a tethering factor at the plasma membrane for vesicles. Guanosine Triphosphate RAS like proto-oncogene A Homo sapiens
2 We generated an antibody against Sec5-RBD, which abolished the interaction between GTP-Ral and the exocyst complex in vitro. Guanosine Triphosphate RAS like proto-oncogene A Homo sapiens