Pub. Date : 2003 Jul 1
PMID : 12839989
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The Sec5 subunit of the mammalian sec6/8 complex binds Ral in a GTP-dependent manner. | Guanosine Triphosphate | RAS like proto-oncogene A | Homo sapiens |
| 2 | Here we report the crystal structure of the complex between the Ral-binding domain of Sec5 and RalA bound to a non-hydrolyzable GTP analog (GppNHp) at 2.1 A resolution, providing the first structural insights into the mechanism and specificity of sec6/8 regulation. | Guanosine Triphosphate | RAS like proto-oncogene A | Homo sapiens |