Title : Tyrosine phosphorylation of RalGDS by c-Met receptor blocks its interaction with Ras.

Pub. Date : 2016 Nov 18

PMID : 27773821






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 RalGDS is a guanine nucleotide exchange factor that promotes the active GTP-bound form of Ral GTPases, RalA and RalB. Guanosine Triphosphate RAS like proto-oncogene A Homo sapiens
2 GTP-bound Ras has the capacity to activate Ral GTPases at least in part by binding to the C-terminal Ras-binding domain (RBD) of RalGDS and directing the protein to Ral GTPases in the plasma membrane. Guanosine Triphosphate RAS like proto-oncogene A Homo sapiens
3 GTP-bound Ras has the capacity to activate Ral GTPases at least in part by binding to the C-terminal Ras-binding domain (RBD) of RalGDS and directing the protein to Ral GTPases in the plasma membrane. Guanosine Triphosphate RAS like proto-oncogene A Homo sapiens