Glutathione

glutamate-cysteine ligase, modifier subunit ; Mus musculus







69 Article(s)
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Pub. Year
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1 34953454 Persistence of improved glucose homeostasis in Gclm null mice with age and cadmium treatment. 2022 Feb 4
2 35238901 Glutathione deficiency decreases lipid droplet stores and increases reactive oxygen species in mouse oocytes†. 2022 Jun 13 1
3 35447412 Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis. 2022 Jun 1
4 33505589 Nrf2-ARE Signaling Partially Attenuates Lipopolysaccharide-Induced Mammary Lesions via Regulation of Oxidative and Organelle Stresses but Not Inflammatory Response in Mice. 2021 1
5 31950131 Antioxidant supplementation partially rescues accelerated ovarian follicle loss, but not oocyte quality, of glutathione-deficient mice†. 2020 Apr 24 2
6 32203083 FSHR ablation induces depression-like behaviors. 2020 Aug 1
7 32942603 Honokiol Protects the Kidney from Renal Ischemia and Reperfusion Injury by Upregulating the Glutathione Biosynthetic Enzymes. 2020 Sep 15 1
8 30794799 Hepatic metabolic adaptation in a murine model of glutathione deficiency. 2019 Apr 25 3
9 31129139 Honokiol alleviates acetaminophen-induced hepatotoxicity via decreasing generation of acetaminophen-protein adducts in liver. 2019 Aug 1 1
10 29307609 Decreased glutathione levels cause overt motor neuron degeneration in hSOD1WT over-expressing mice. 2018 Apr 1
11 29800640 Glutathione deficiency sensitizes cultured embryonic mouse ovaries to benzo[a]pyrene-induced germ cell apoptosis. 2018 Aug 1 3
12 27733046 Targeting of the Glutathione, Thioredoxin, and Nrf2 Antioxidant Systems in Head and Neck Cancer. 2017 Jul 10 1
13 28279692 Ovarian effects of prenatal exposure to benzo[a]pyrene: Roles of embryonic and maternal glutathione status. 2017 Apr 2
14 28664650 Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine-to-glutamate ratio and myo-inositol concentration in the mouse frontal cortex. 2017 Sep 1
15 26486419 Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes. 2016 Feb 1
16 27148080 Glutamate Cysteine Ligase-Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage. 2016 2
17 27262586 Low levels of glutathione are sufficient for survival of keratinocytes after UV irradiation and for healing of mouse skin wounds. 2016 Aug 1
18 27596734 The pulmonary inflammatory response to multiwalled carbon nanotubes is influenced by gender and glutathione synthesis. 2016 Oct 2
19 27865893 Sex and genetic differences in the effects of acute diesel exhaust exposure on inflammation and oxidative stress in mouse brain. 2016 Dec 30 1
20 25797475 The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice. 2015 May 1
21 26083875 Glutamate Cysteine Ligase Modifier Subunit (Gclm) Null Mice Have Increased Ovarian Oxidative Stress and Accelerated Age-Related Ovarian Failure. 2015 Sep 4
22 26433393 Glutathione Deficit Affects the Integrity and Function of the Fimbria/Fornix and Anterior Commissure in Mice: Relevance for Schizophrenia. 2015 Oct 3 1
23 24291350 Reprint of "In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective". 2014 Oct 15 1
24 24563856 Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6. 2014 2
25 23129588 Chronic depletion of glutathione exacerbates ventricular remodelling and dysfunction in the pressure-overloaded heart. 2013 Feb 1 2
26 23135907 Glutathione-deficient mice have increased sensitivity to transplacental benzo[a]pyrene-induced premature ovarian failure and ovarian tumorigenesis. 2013 Jan 15 3
27 23136969 Activation of de novo GSH synthesis pathway in mouse spleen after long term low-dose γ-ray irradiation. 2013 Feb 1
28 23315585 Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathione. 2013 Apr 2
29 23704229 Glutathione deficiency in Gclm null mice results in complex I inhibition and dopamine depletion following paraquat administration. 2013 Aug 8
30 23715558 Defective Nrf2-dependent redox signalling contributes to microvascular dysfunction in type 2 diabetes. 2013 Oct 1 3
31 23724032 The glutathione synthesis gene Gclm modulates amphiphilic polymer-coated CdSe/ZnS quantum dot-induced lung inflammation in mice. 2013 1
32 23748015 Effects of side-stream tobacco smoke and smoke extract on glutathione- and oxidative DNA damage repair-deficient mice and blood cells. 2013 Sep 1
33 23787995 Functional significance of glutamate-cysteine ligase modifier for erythrocyte survival in vitro and in vivo. 2013 Oct 2
34 23808636 Glutathione (GSH) and the GSH synthesis gene Gclm modulate plasma redox and vascular responses to acute diesel exhaust inhalation in mice. 2013 Jul 2
35 24107266 In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective. 2013 Nov 25 1
36 21945305 N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development. 2012 Jun 1 1
37 22033334 Behavioral phenotyping of glutathione-deficient mice: relevance to schizophrenia and bipolar disorder. 2012 Jan 15 3
38 22082335 Glutathione-deficient mice are susceptible to TCDD-Induced hepatocellular toxicity but resistant to steatosis. 2012 Jan 13 5
39 22253057 Increased sensitivity to testicular toxicity of transplacental benzo[a]pyrene exposure in male glutamate cysteine ligase modifier subunit knockout (Gclm-/-) mice. 2012 Mar 4
40 22580179 Effect of chronic glutathione deficiency on the behavioral phenotype of Gclm-/- knockout mice. 2012 Jul 4
41 22824862 Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice. 2012 Sep 15 2
42 21558310 Lack of maternal glutamate cysteine ligase modifier subunit (Gclm) decreases oocyte glutathione concentrations and disrupts preimplantation development in mice. 2011 Jul 3
43 21559092 Behavioral Characterization of GCLM-Knockout Mice, a Model for Enhanced Susceptibility to Oxidative Stress. 2011 2
44 21600285 Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model. 2011 Sep 2
45 21829542 Altered glycogen metabolism in cultured astrocytes from mice with chronic glutathione deficit; relevance for neuroenergetics in schizophrenia. 2011 1
46 21967497 Heterozygosity in the glutathione synthesis gene Gclm increases sensitivity to diesel exhaust particulate induced lung inflammation in mice. 2011 Oct 1
47 19837697 Mice lacking the glutamate-cysteine ligase modifier subunit are susceptible to myocardial ischaemia-reperfusion injury. 2010 Mar 1 5
48 20006689 Enhanced glutathione biosynthetic capacity promotes resistance to As3+-induced apoptosis. 2010 Mar 1 1
49 20417186 Glutathione deficient C57BL/6J mice are not sensitized to ozone-induced lung injury. 2010 May 28 1
50 19150461 Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71. 2009 Mar 3