Glutathione

glutamate-cysteine ligase, modifier subunit ; Mus musculus







69 Article(s)
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51 19200344 Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells. 2009 Apr 1
52 19328227 Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes. 2009 Jun 15 1
53 19427898 Early onset senescence occurs when fibroblasts lack the glutamate-cysteine ligase modifier subunit. 2009 Aug 15 2
54 23045016 Glutamate cysteine ligase (GCL) transgenic and gene-targeted mice for controlling glutathione synthesis. 2009 Feb 1
55 18262489 Liver betaine-homocysteine S-methyltransferase activity undergoes a redox switch at the active site zinc. 2008 Apr 1 1
56 18642143 Modulating GSH synthesis using glutamate cysteine ligase transgenic and gene-targeted mice. 2008 2
57 17084875 Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. 2007 Mar 2
58 17584759 Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice. 2007 Oct 1
59 17623891 Over expression of glutamate cysteine ligase increases cellular resistance to H2O2-induced DNA single-strand breaks. 2007 Sep 1
60 17804861 Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells. 2007 Dec 1
61 16014739 Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status. 2005 Oct 2
62 16081425 Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels. 2005 Oct 7 2
63 14871475 Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress. 2004 Mar 1 2
64 15288121 Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosis. 2004 Sep 1 1
65 12600891 Induction of glutathione synthesis in macrophages by oxidized low-density lipoproteins is mediated by consensus antioxidant response elements. 2003 Mar 7 1
66 12384496 Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response. 2002 Dec 20 3
67 11439218 Tissue specific changes in the expression of glutamate-cysteine ligase mRNAs in mice exposed to methylmercury. 2001 Jun 20 2
68 11514103 Localization of glutamate-cysteine ligase mRNA and protein in mouse kidney and induction with methylmercury. 2001 Aug 6 1
69 11118286 Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous. 2000 Dec 20 1